Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ITGB4Integrin subunit beta 4. (1597 aa)    
Predicted Functional Partners:
ITGA6
Integrin subunit alpha 6.
   
 0.999
ITGA7
Integrin subunit alpha 7.
   
 0.995
ITGA3
Integrin subunit alpha 3.
   
 0.991
PLEC
Plectin.
  
 0.981
ITGA5
Integrin subunit alpha 5.
   
 0.978
ITGAV
Integrin subunit alpha V.
   
 0.978
LAMB3
Laminin subunit beta 3.
   
 0.977
ITGA2
Integrin subunit alpha 2.
   
 0.976
ITGA4
Integrin subunit alpha 4.
   
 0.972
ITGA1
Integrin subunit alpha 1.
   
 0.970
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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