Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1505 aa)    
Predicted Functional Partners:
MAP2K4
Mitogen-activated protein kinase kinase 4.
    
 0.993
MAP2K7
Mitogen-activated protein kinase kinase 7.
    
 0.993
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
   
 0.990
TRAF6
TNF receptor associated factor 6.
    
 0.990
MAPK10
Mitogen-activated protein kinase 10.
    
 0.989
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
   
 0.988
ENSPCAP00000010754
annotation not available
    
 0.988
ENSPCAP00000011509
annotation not available
   
 0.983
TRAF1
TNF receptor associated factor 1.
   
 0.983
TRAF3
TNF receptor associated factor 3.
   
 0.973
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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