Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
RASGEF1ARasGEF domain family member 1A. (489 aa)    
Predicted Functional Partners:
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
    
 0.723
GRB2
Growth factor receptor bound protein 2.
     
 0.637
RASA1
RAS p21 protein activator 1.
    
 
 0.634
NF1
Neurofibromin 1.
      
 0.584
ENSPCAP00000014701
annotation not available
      
 0.584
SOS2
SOS Ras/Rho guanine nucleotide exchange factor 2.
    
 0.577
TIAM1
TIAM Rac1 associated GEF 1.
      
 0.572
RASGRP1
RAS guanyl releasing protein 1.
    
 0.572
SBNO1
Strawberry notch homolog 1.
      
 0.571
RIOK1
RIO kinase 1.
      
 0.566
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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