Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTK7Protein tyrosine kinase 7 (inactive). (1012 aa)    
Predicted Functional Partners:
ERBB2
Erb-b2 receptor tyrosine kinase 2.
   
  0.923
MST1R
Macrophage stimulating 1 receptor.
    
 0.912
MET
MET proto-oncogene, receptor tyrosine kinase.
    
 0.912
PLCG1
Phospholipase C gamma 1.
    
 0.877
PLCG2
Phospholipase C gamma 2.
    
 0.877
CORIN
Corin, serine peptidase.
    
 0.860
HABP2
Hyaluronan binding protein 2.
    
 0.847
HGFAC
HGF activator.
    
 0.847
F12
Coagulation factor XII.
    
 0.847
NGFR
Nerve growth factor receptor.
   
 0.822
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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