Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LRP6LDL receptor related protein 6. (1611 aa)    
Predicted Functional Partners:
AXIN1
Axin 1.
    
 0.998
SOST
Sclerostin.
    
 0.997
DKK1
Dickkopf WNT signaling pathway inhibitor 1.
    
 0.997
WNT3
Wnt family member 3.
    
 0.997
WNT1
Wnt family member 1.
    
 0.996
CTNNB1
Catenin beta 1.
    
 0.995
DVL1
Dishevelled segment polarity protein 1.
    
 0.994
AXIN2
Axin 2.
    
 0.994
ENSPCAP00000006901
annotation not available
   
 0.992
FZD1
Frizzled class receptor 1.
    
 0.990
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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