close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMC5Structural maintenance of chromosomes 5. (1102 aa)    
Predicted Functional Partners:
NSMCE2
NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase.
    
 0.999
NSMCE4A
NSE4 homolog A, SMC5-SMC6 complex component.
   
 0.999
NSMCE1
NSE1 homolog, SMC5-SMC6 complex component.
    
 0.999
SMC6
Structural maintenance of chromosomes 6.
   
0.999
MAGED2
MAGE family member D2.
   
 0.976
ENSPCAP00000007676
annotation not available
   
 0.968
ENSPCAP00000009238
annotation not available
   
 0.968
RAD21
RAD21 cohesin complex component.
   
 0.956
NIPBL
NIPBL cohesin loading factor.
   
 0.956
ENSPCAP00000008776
annotation not available
   
 0.947
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.