Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTPN1Protein tyrosine phosphatase non-receptor type 1. (424 aa)    
Predicted Functional Partners:
INSR
Insulin receptor.
    
 0.997
JAK2
Janus kinase 2.
   
 0.996
IGF1R
Insulin like growth factor 1 receptor.
    
 0.992
MET
MET proto-oncogene, receptor tyrosine kinase.
    
 0.991
INSRR
Insulin receptor related receptor.
    
 0.985
EGFR
Epidermal growth factor receptor.
    
 0.978
JAK3
Janus kinase 3.
   
 0.973
TYK2
Tyrosine kinase 2.
   
 0.972
BCAR1
BCAR1 scaffold protein, Cas family member.
    
 
 0.959
ENSPCAP00000009332
annotation not available
    
 0.952
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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