Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HELQHelicase, POLQ like. (1098 aa)    
Predicted Functional Partners:
POLN
DNA polymerase nu.
 
  
 
 0.956
FANCD2
FA complementation group D2.
   
 0.948
POLA1
DNA polymerase alpha 1, catalytic subunit.
   
 0.849
REV3L
REV3 like, DNA directed polymerase zeta catalytic subunit.
   
 0.763
ENSPCAP00000006644
annotation not available
   
 
 0.757
ENSPCAP00000010722
annotation not available
   
 
 0.757
FANCI
FA complementation group I.
   
 0.737
RAD51
RAD51 recombinase.
  
 
 0.736
FEN1
Flap structure-specific endonuclease 1.
  
 
 0.736
FANCL
FA complementation group L.
     
 0.716
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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