close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HELQHelicase, POLQ like. (1098 aa)    
Predicted Functional Partners:
POLN
DNA polymerase nu.
 
  
 
 0.837
ENSPCAP00000010722
annotation not available
   
 
 0.832
FANCD2
FA complementation group D2.
   
 0.814
ENSPCAP00000012584
annotation not available
   
 0.812
FEN1
Flap structure-specific endonuclease 1.
  
 
 0.767
TWNK
Twinkle mtDNA helicase.
     
 0.759
ENSPCAP00000002344
annotation not available
    
 0.755
EXO1
Exonuclease 1.
  
 
 0.755
MRE11
MRE11 homolog, double strand break repair nuclease.
  
 0.745
FANCI
FA complementation group I.
   
 0.690
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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