Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SETBP1SET binding protein 1. (1540 aa)    
Predicted Functional Partners:
SETD2
SET domain containing 2, histone lysine methyltransferase.
   
 
 0.847
PHF6
PHD finger protein 6.
   
 0.815
ENSPCAP00000013473
annotation not available
     
 0.764
DOT1L
DOT1 like histone lysine methyltransferase.
    
 0.749
ENSPCAP00000012016
annotation not available
    
 0.749
CSF3R
Colony stimulating factor 3 receptor.
     
 0.737
SUZ12
SUZ12 polycomb repressive complex 2 subunit.
    
 0.720
EZH2
Enhancer of zeste 2 polycomb repressive complex 2 subunit.
     
 0.719
KDM6B
Lysine demethylase 6B.
   
 0.718
ENSPCAP00000014192
annotation not available
   
 0.718
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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