close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SP1Sp1 transcription factor. (701 aa)    
Predicted Functional Partners:
EP300
E1A binding protein p300.
   
 0.993
ENSPCAP00000014347
annotation not available
    
 0.993
ESR2
Estrogen receptor 2.
    
 0.973
CREBBP
CREB binding protein.
   
 0.968
TP53
Tumor protein p53.
    
 0.958
ENSPCAP00000010754
annotation not available
    
 0.924
MAPK10
Mitogen-activated protein kinase 10.
    
 0.924
MAPK12
Mitogen-activated protein kinase 12.
    
 0.916
MAPK13
Mitogen-activated protein kinase 13.
    
 0.916
PRKACA
Protein kinase cAMP-activated catalytic subunit alpha.
    
 0.914
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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