close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCLS1Hematopoietic cell-specific Lyn substrate 1. (477 aa)    
Predicted Functional Partners:
WAS
WASP actin nucleation promoting factor.
   
 0.973
TJP1
Tight junction protein 1.
    
 0.963
DNM3
Dynamin 3.
    
 0.956
DNM2
Dynamin 2.
   
 0.939
DNM1
Dynamin 1.
   
 0.939
SRC
SRC proto-oncogene, non-receptor tyrosine kinase.
   
 0.937
ACTR2
Actin related protein 2.
   
 0.937
WHAMM
WASP homolog associated with actin, golgi membranes and microtubules.
   
 0.921
PTK2
Protein tyrosine kinase 2.
    
 0.905
CTTN
Cortactin.
  
  
0.889
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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