Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HECTD2HECT domain E3 ubiquitin protein ligase 2. (706 aa)    
Predicted Functional Partners:
TP53
Tumor protein p53.
    
 0.803
TSC2
TSC complex subunit 2.
    
 0.727
TSC1
TSC complex subunit 1.
    
 0.648
ENSPCAP00000007408
annotation not available
   
 0.648
UBE2L6
Ubiquitin conjugating enzyme E2 L6.
   
 0.648
UBC
Ubiquitin C.
    
 0.644
CTNNB1
Catenin beta 1.
    
 0.638
JUP
Junction plakoglobin.
    
 0.638
TRIP12
Thyroid hormone receptor interactor 12.
   
 
 0.625
CRB3
Crumbs cell polarity complex component 3.
     
  0.619
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.