INSR protein (Procavia capensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

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Co-occurrence

Co-expression

Experiments

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[Homology]

Score

INSR

Insulin receptor. (1287 aa)

Predicted Functional Partners:

INS-IGF2

0.999

IGF1R

0.999

PTPN1

0.997

ENSPCAP00000007516

0.997

PIK3R1

0.996

GRB10

0.996

ENSPCAP00000009332

0.996

ENSPCAP00000011350

0.993

GRB14

0.990

ENSPCAP00000012906

0.988

Your Current Organism:

Procavia capensis

NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax

Export your current network:

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPCAP00000007516	ENSPCAP00000009332	ENSPCAP00000007516	ENSPCAP00000009332	annotation not available	annotation not available	0.787
ENSPCAP00000007516	ENSPCAP00000011350	ENSPCAP00000007516	ENSPCAP00000011350	annotation not available	annotation not available	0.908
ENSPCAP00000007516	GRB10	ENSPCAP00000007516	ENSPCAP00000007943	annotation not available	Growth factor receptor bound protein 10.	0.437
ENSPCAP00000007516	IGF1R	ENSPCAP00000007516	ENSPCAP00000015555	annotation not available	Insulin like growth factor 1 receptor.	0.999
ENSPCAP00000007516	INS-IGF2	ENSPCAP00000007516	ENSPCAP00000012156	annotation not available	INS-IGF2 readthrough.	0.979
ENSPCAP00000007516	INSR	ENSPCAP00000007516	ENSPCAP00000004897	annotation not available	Insulin receptor.	0.997
ENSPCAP00000007516	PIK3R1	ENSPCAP00000007516	ENSPCAP00000004051	annotation not available	Phosphoinositide-3-kinase regulatory subunit 1.	0.546
ENSPCAP00000009332	ENSPCAP00000007516	ENSPCAP00000009332	ENSPCAP00000007516	annotation not available	annotation not available	0.787
ENSPCAP00000009332	ENSPCAP00000011350	ENSPCAP00000009332	ENSPCAP00000011350	annotation not available	annotation not available	0.743
ENSPCAP00000009332	ENSPCAP00000012906	ENSPCAP00000009332	ENSPCAP00000012906	annotation not available	annotation not available	0.981
ENSPCAP00000009332	GRB10	ENSPCAP00000009332	ENSPCAP00000007943	annotation not available	Growth factor receptor bound protein 10.	0.856
ENSPCAP00000009332	GRB14	ENSPCAP00000009332	ENSPCAP00000000378	annotation not available	Growth factor receptor bound protein 14.	0.723
ENSPCAP00000009332	IGF1R	ENSPCAP00000009332	ENSPCAP00000015555	annotation not available	Insulin like growth factor 1 receptor.	0.995
ENSPCAP00000009332	INS-IGF2	ENSPCAP00000009332	ENSPCAP00000012156	annotation not available	INS-IGF2 readthrough.	0.962
ENSPCAP00000009332	INSR	ENSPCAP00000009332	ENSPCAP00000004897	annotation not available	Insulin receptor.	0.996
ENSPCAP00000009332	PIK3R1	ENSPCAP00000009332	ENSPCAP00000004051	annotation not available	Phosphoinositide-3-kinase regulatory subunit 1.	0.994
ENSPCAP00000009332	PTPN1	ENSPCAP00000009332	ENSPCAP00000004467	annotation not available	Protein tyrosine phosphatase non-receptor type 1.	0.952
ENSPCAP00000011350	ENSPCAP00000007516	ENSPCAP00000011350	ENSPCAP00000007516	annotation not available	annotation not available	0.908
ENSPCAP00000011350	ENSPCAP00000009332	ENSPCAP00000011350	ENSPCAP00000009332	annotation not available	annotation not available	0.743
ENSPCAP00000011350	GRB10	ENSPCAP00000011350	ENSPCAP00000007943	annotation not available	Growth factor receptor bound protein 10.	0.563