close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FOXO1Forkhead box O1. (414 aa)    
Predicted Functional Partners:
SIRT1
Sirtuin 1.
    
 0.974
AKT3
AKT serine/threonine kinase 3.
    
 0.948
AKT1
AKT serine/threonine kinase 1.
    
 0.948
USP7
Ubiquitin specific peptidase 7.
   
 0.942
SGK2
Serum/glucocorticoid regulated kinase 2.
    
 0.938
SGK1
Serum/glucocorticoid regulated kinase 1.
    
 0.938
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
    
 0.936
PPARGC1A
PPARG coactivator 1 alpha.
    
 0.933
SMAD2
SMAD family member 2.
    
 0.932
ENSPCAP00000007856
annotation not available
    
 0.927
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.