| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| OXB_1022 | OXB_1023 | OXB_1022 | OXB_1023 | Pur operon repressor. | Endoribonuclease l-psp. | 0.862 |
| OXB_1022 | glmU | OXB_1022 | OXB_1025 | Pur operon repressor. | Bifunctional n-acetylglucosamine-1-phosphate; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.778 |
| OXB_1022 | ispE | OXB_1022 | OXB_1021 | Pur operon repressor. | 4-diphosphocytidyl-2-C-methyl-D-erythritol; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.684 |
| OXB_1022 | prs | OXB_1022 | OXB_1026 | Pur operon repressor. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.621 |
| OXB_1022 | spoVG | OXB_1022 | OXB_1024 | Pur operon repressor. | Regulatory protein spovg; Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation. | 0.534 |
| OXB_1023 | OXB_1022 | OXB_1023 | OXB_1022 | Endoribonuclease l-psp. | Pur operon repressor. | 0.862 |
| OXB_1023 | ispE | OXB_1023 | OXB_1021 | Endoribonuclease l-psp. | 4-diphosphocytidyl-2-C-methyl-D-erythritol; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.646 |
| OXB_1023 | spoVG | OXB_1023 | OXB_1024 | Endoribonuclease l-psp. | Regulatory protein spovg; Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation. | 0.589 |
| glmU | OXB_1022 | OXB_1025 | OXB_1022 | Bifunctional n-acetylglucosamine-1-phosphate; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | Pur operon repressor. | 0.778 |
| glmU | ispE | OXB_1025 | OXB_1021 | Bifunctional n-acetylglucosamine-1-phosphate; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 4-diphosphocytidyl-2-C-methyl-D-erythritol; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.463 |
| glmU | prs | OXB_1025 | OXB_1026 | Bifunctional n-acetylglucosamine-1-phosphate; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.979 |
| glmU | pth | OXB_1025 | OXB_1028 | Bifunctional n-acetylglucosamine-1-phosphate; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.458 |
| glmU | spoVG | OXB_1025 | OXB_1024 | Bifunctional n-acetylglucosamine-1-phosphate; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | Regulatory protein spovg; Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation. | 0.546 |
| ispE | OXB_1022 | OXB_1021 | OXB_1022 | 4-diphosphocytidyl-2-C-methyl-D-erythritol; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | Pur operon repressor. | 0.684 |
| ispE | OXB_1023 | OXB_1021 | OXB_1023 | 4-diphosphocytidyl-2-C-methyl-D-erythritol; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | Endoribonuclease l-psp. | 0.646 |
| ispE | glmU | OXB_1021 | OXB_1025 | 4-diphosphocytidyl-2-C-methyl-D-erythritol; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | Bifunctional n-acetylglucosamine-1-phosphate; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.463 |
| ispE | spoVG | OXB_1021 | OXB_1024 | 4-diphosphocytidyl-2-C-methyl-D-erythritol; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | Regulatory protein spovg; Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation. | 0.437 |
| prs | OXB_1022 | OXB_1026 | OXB_1022 | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | Pur operon repressor. | 0.621 |
| prs | glmU | OXB_1026 | OXB_1025 | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | Bifunctional n-acetylglucosamine-1-phosphate; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.979 |
| prs | pth | OXB_1026 | OXB_1028 | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.571 |