Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pxpALamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. (251 aa)    
Predicted Functional Partners:
OXB_2158
Allophanate hydrolase subunit 1.
  
 0.997
OXB_2157
Allophanate hydrolase subunit 2.
  
 0.986
OXB_2160
NRAMP family Mn2+ transporter.
 
  
 0.980
OXB_2162
Protein ycsi; Belongs to the D-glutamate cyclase family.
 
  
 0.809
OXB_2220
Glutamine synthetase.
   
 
  0.809
OXB_0022
Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
  0.803
OXB_3457
Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
  0.803
rocA
1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. RocA subfamily.
     
  0.800
purQ
Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...]
     
  0.800
OXB_2155
Transcriptional regulator.
  
  
 0.738
Your Current Organism:
Bacillus sp. OxB1
NCBI taxonomy Id: 98228
Other names: B. sp. OxB-1, Bacillus sp. OxB-1
Server load: high (88%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.