STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OXB_3545Multifunctional enzyme siroheme synthase cysg. (207 aa)    
Predicted Functional Partners:
OXB_3547
uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
  
  0.997
OXB_1223
uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
 
  
  0.981
OXB_3546
Sirohydrochlorin cobaltochelatase.
    
  0.976
OXB_1226
Cobalt-precorrin-2 C(20)-methyltransferase; Belongs to the precorrin methyltransferase family.
     
  0.900
OXB_1231
Sirohydrochlorin cobaltochelatase.
     
  0.900
cysC
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
       0.735
sat
Sulfate adenylyltransferase; Belongs to the sulfate adenylyltransferase family.
       0.719
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
     0.687
cysH
Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
 
     0.684
OXB_1225
Cobalt-precorrin-4 C(11)-methyltransferase; Belongs to the precorrin methyltransferase family.
 
     0.546
Your Current Organism:
Bacillus sp. OxB1
NCBI taxonomy Id: 98228
Other names: B. sp. OxB-1, Bacillus sp. OxB-1
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.