node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALDOA | ALDOB | ENSSSCP00000055491 | ENSSSCP00000070741 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | 0.955 |
ALDOA | ALDOC | ENSSSCP00000055491 | ENSSSCP00000052799 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | 0.953 |
ALDOA | BPGM | ENSSSCP00000055491 | ENSSSCP00000054034 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. | 0.918 |
ALDOA | GAPDH | ENSSSCP00000055491 | ENSSSCP00000035519 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] | 0.987 |
ALDOA | GPI | ENSSSCP00000055491 | ENSSSCP00000003094 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Glucose-6-phosphate isomerase; In the cytoplasm, catalyzes the conversion of glucose-6- phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis (By similarity). Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion (By similarity). | 0.951 |
ALDOA | PGK1 | ENSSSCP00000055491 | ENSSSCP00000013238 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Phosphoglycerate kinase 1; Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3- diphosphoglycerate to 3-phosphoglycerate. In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein). May play a role in sperm motility. | 0.854 |
ALDOA | PGK2 | ENSSSCP00000055491 | ENSSSCP00000045543 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Phosphoglycerate kinase 2; Essential for sperm motility and male fertility but is not required for the completion of spermatogenesis. Belongs to the phosphoglycerate kinase family. | 0.776 |
ALDOA | TALDO1 | ENSSSCP00000055491 | ENSSSCP00000058258 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. | 0.959 |
ALDOA | TPI1 | ENSSSCP00000055491 | ENSSSCP00000000730 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Triosephosphate isomerase; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis. | 0.990 |
ALDOB | ALDOA | ENSSSCP00000070741 | ENSSSCP00000055491 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | 0.955 |
ALDOB | ALDOC | ENSSSCP00000070741 | ENSSSCP00000052799 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | 0.925 |
ALDOB | BPGM | ENSSSCP00000070741 | ENSSSCP00000054034 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. | 0.924 |
ALDOB | GAPDH | ENSSSCP00000070741 | ENSSSCP00000035519 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] | 0.980 |
ALDOB | GPI | ENSSSCP00000070741 | ENSSSCP00000003094 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Glucose-6-phosphate isomerase; In the cytoplasm, catalyzes the conversion of glucose-6- phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis (By similarity). Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion (By similarity). | 0.943 |
ALDOB | PGK1 | ENSSSCP00000070741 | ENSSSCP00000013238 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Phosphoglycerate kinase 1; Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3- diphosphoglycerate to 3-phosphoglycerate. In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein). May play a role in sperm motility. | 0.699 |
ALDOB | PGK2 | ENSSSCP00000070741 | ENSSSCP00000045543 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Phosphoglycerate kinase 2; Essential for sperm motility and male fertility but is not required for the completion of spermatogenesis. Belongs to the phosphoglycerate kinase family. | 0.746 |
ALDOB | TALDO1 | ENSSSCP00000070741 | ENSSSCP00000058258 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. | 0.956 |
ALDOB | TPI1 | ENSSSCP00000070741 | ENSSSCP00000000730 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Triosephosphate isomerase; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis. | 0.985 |
ALDOC | ALDOA | ENSSSCP00000052799 | ENSSSCP00000055491 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | 0.953 |
ALDOC | ALDOB | ENSSSCP00000052799 | ENSSSCP00000070741 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | 0.925 |