SYCE3 protein (Sus scrofa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

SYCE3

Synaptonemal complex central element protein 3. (109 aa)

Predicted Functional Partners:

SYCE2

0.953

SYCE1

0.952

TEX12

0.902

SYCP3

0.856

FAM71D

0.828

HORMAD1

0.766

STAG3

0.765

REC8

0.734

SYCP2

0.715

PRDM6

0.710

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FAM71D	SYCE3	ENSSSCP00000073629	ENSSSCP00000001031	Family with sequence similarity 71 member D.	Synaptonemal complex central element protein 3.	0.828
FAM71D	SYCP3	ENSSSCP00000073629	ENSSSCP00000034487	Family with sequence similarity 71 member D.	Synaptonemal complex protein 3.	0.553
HORMAD1	REC8	ENSSSCP00000007090	ENSSSCP00000002187	HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...]	Meiotic recombination protein REC8 homolog.	0.869
HORMAD1	STAG3	ENSSSCP00000007090	ENSSSCP00000008171	HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...]	Stromal antigen 3.	0.757
HORMAD1	SYCE1	ENSSSCP00000007090	ENSSSCP00000011492	HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...]	Synaptonemal complex central element protein 1.	0.784
HORMAD1	SYCE2	ENSSSCP00000007090	ENSSSCP00000014609	HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...]	Synaptonemal complex central element protein 2.	0.597
HORMAD1	SYCE3	ENSSSCP00000007090	ENSSSCP00000001031	HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...]	Synaptonemal complex central element protein 3.	0.766
HORMAD1	SYCP3	ENSSSCP00000007090	ENSSSCP00000034487	HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...]	Synaptonemal complex protein 3.	0.855
HORMAD1	TEX12	ENSSSCP00000007090	ENSSSCP00000027044	HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...]	Testis expressed 12.	0.562
PRDM6	SYCE3	ENSSSCP00000015146	ENSSSCP00000001031	PR/SET domain 6.	Synaptonemal complex central element protein 3.	0.710
REC8	HORMAD1	ENSSSCP00000002187	ENSSSCP00000007090	Meiotic recombination protein REC8 homolog.	HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...]	0.869
REC8	STAG3	ENSSSCP00000002187	ENSSSCP00000008171	Meiotic recombination protein REC8 homolog.	Stromal antigen 3.	0.995
REC8	SYCE1	ENSSSCP00000002187	ENSSSCP00000011492	Meiotic recombination protein REC8 homolog.	Synaptonemal complex central element protein 1.	0.826
REC8	SYCE2	ENSSSCP00000002187	ENSSSCP00000014609	Meiotic recombination protein REC8 homolog.	Synaptonemal complex central element protein 2.	0.639
REC8	SYCE3	ENSSSCP00000002187	ENSSSCP00000001031	Meiotic recombination protein REC8 homolog.	Synaptonemal complex central element protein 3.	0.734
REC8	SYCP3	ENSSSCP00000002187	ENSSSCP00000034487	Meiotic recombination protein REC8 homolog.	Synaptonemal complex protein 3.	0.862
REC8	TEX12	ENSSSCP00000002187	ENSSSCP00000027044	Meiotic recombination protein REC8 homolog.	Testis expressed 12.	0.562
STAG3	HORMAD1	ENSSSCP00000008171	ENSSSCP00000007090	Stromal antigen 3.	HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...]	0.757
STAG3	REC8	ENSSSCP00000008171	ENSSSCP00000002187	Stromal antigen 3.	Meiotic recombination protein REC8 homolog.	0.995
STAG3	SYCE1	ENSSSCP00000008171	ENSSSCP00000011492	Stromal antigen 3.	Synaptonemal complex central element protein 1.	0.821