close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SYCE3Synaptonemal complex central element protein 3. (109 aa)    
Predicted Functional Partners:
SYCE1
Synaptonemal complex central element protein 1.
    
 
 0.960
SYCE2
Synaptonemal complex central element protein 2.
    
 
 0.907
TEX12
Testis expressed 12.
      
 0.851
SYCP3
Synaptonemal complex protein 3.
      
 0.836
FAM71D
Family with sequence similarity 71 member D.
      
 0.802
HORMAD1
HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...]
      
 0.800
REC8
Meiotic recombination protein REC8 homolog.
      
 0.798
SPO11
SPO11 meiotic protein covalently bound to DSB-like (S. cerevisiae).
      
 0.651
STAG3
Stromal antigen 3.
      
 0.617
UBR7
UBR-type domain-containing protein.
      
 0.611
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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