CRELD2 protein (Sus scrofa) - STRING interaction network

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[Homology]

Score

CRELD2

Cysteine rich with EGF like domains 2. (423 aa)

Predicted Functional Partners:

MANF

0.906

PDIA4

0.869

MATN3

0.825

DNAJB11

0.780

HYOU1

0.759

COPB2

0.723

PDIA6

0.712

HSPA5

0.706

SDF2

0.639

HSP90B1

0.631

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COPB2	CRELD2	ENSSSCP00000033611	ENSSSCP00000001049	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	Cysteine rich with EGF like domains 2.	0.723
COPB2	HSP90B1	ENSSSCP00000033611	ENSSSCP00000000906	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. Belongs to the heat shock protein 90 family.	0.491
COPB2	MATN3	ENSSSCP00000033611	ENSSSCP00000009174	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	Matrilin 3.	0.433
CRELD2	COPB2	ENSSSCP00000001049	ENSSSCP00000033611	Cysteine rich with EGF like domains 2.	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.723
CRELD2	DNAJB11	ENSSSCP00000001049	ENSSSCP00000012569	Cysteine rich with EGF like domains 2.	DnaJ homolog subfamily B member 11.	0.780
CRELD2	HSP90B1	ENSSSCP00000001049	ENSSSCP00000000906	Cysteine rich with EGF like domains 2.	Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. Belongs to the heat shock protein 90 family.	0.631
CRELD2	HSPA5	ENSSSCP00000001049	ENSSSCP00000055982	Cysteine rich with EGF like domains 2.	Endoplasmic reticulum chaperone BiP; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity). Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate (By similarity). Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). In the unstressed endoplasmic reticulum, recruited by DNAJB9/ERdj4 to the luminal region of ERN1/IRE1, leading to dis [...]	0.706
CRELD2	HYOU1	ENSSSCP00000001049	ENSSSCP00000037024	Cysteine rich with EGF like domains 2.	Hypoxia up-regulated 1.	0.759
CRELD2	MANF	ENSSSCP00000001049	ENSSSCP00000069999	Cysteine rich with EGF like domains 2.	Uncharacterized protein.	0.906
CRELD2	MATN3	ENSSSCP00000001049	ENSSSCP00000009174	Cysteine rich with EGF like domains 2.	Matrilin 3.	0.825
CRELD2	PDIA4	ENSSSCP00000001049	ENSSSCP00000016385	Cysteine rich with EGF like domains 2.	Protein disulfide-isomerase.	0.869
CRELD2	PDIA6	ENSSSCP00000001049	ENSSSCP00000009202	Cysteine rich with EGF like domains 2.	Uncharacterized protein; Belongs to the protein disulfide isomerase family.	0.712
CRELD2	SDF2	ENSSSCP00000001049	ENSSSCP00000018831	Cysteine rich with EGF like domains 2.	Stromal cell-derived factor 2.	0.639
DNAJB11	CRELD2	ENSSSCP00000012569	ENSSSCP00000001049	DnaJ homolog subfamily B member 11.	Cysteine rich with EGF like domains 2.	0.780
DNAJB11	HSP90B1	ENSSSCP00000012569	ENSSSCP00000000906	DnaJ homolog subfamily B member 11.	Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. Belongs to the heat shock protein 90 family.	0.959
DNAJB11	HSPA5	ENSSSCP00000012569	ENSSSCP00000055982	DnaJ homolog subfamily B member 11.	Endoplasmic reticulum chaperone BiP; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity). Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate (By similarity). Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). In the unstressed endoplasmic reticulum, recruited by DNAJB9/ERdj4 to the luminal region of ERN1/IRE1, leading to dis [...]	0.987
DNAJB11	HYOU1	ENSSSCP00000012569	ENSSSCP00000037024	DnaJ homolog subfamily B member 11.	Hypoxia up-regulated 1.	0.756
DNAJB11	MANF	ENSSSCP00000012569	ENSSSCP00000069999	DnaJ homolog subfamily B member 11.	Uncharacterized protein.	0.944
DNAJB11	PDIA4	ENSSSCP00000012569	ENSSSCP00000016385	DnaJ homolog subfamily B member 11.	Protein disulfide-isomerase.	0.723
DNAJB11	PDIA6	ENSSSCP00000012569	ENSSSCP00000009202	DnaJ homolog subfamily B member 11.	Uncharacterized protein; Belongs to the protein disulfide isomerase family.	0.917