Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GMNNGeminin DNA replication inhibitor. (215 aa)    
Predicted Functional Partners:
CDT1
PI-PLC Y-box domain-containing protein.
   
 0.998
MCM6
DNA helicase; Belongs to the MCM family.
   
 0.942
FZR1
Fizzy and cell division cycle 20 related 1.
   
 0.881
CDK1
Cyclin-dependent kinase 1 isoform 1; Belongs to the protein kinase superfamily.
   
 
 0.862
CDK3
Cyclin dependent kinase 3; Belongs to the protein kinase superfamily.
   
 
 0.832
CDK2
Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.
   
 
 0.822
CCNA1
Cyclin-A1 isoform X1; Belongs to the cyclin family.
   
 
 0.817
CDKN1A
Cyclin dependent kinase inhibitor 1A.
    
 
 0.791
ORC6
Origin recognition complex subunit 6.
   
 
 0.791
CCDC146
Coiled-coil domain containing 146.
    
   0.790
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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