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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100152135Histone H2B; Belongs to the histone H2B family. (127 aa)    
Predicted Functional Partners:
A0A286ZRB3_PIG
Histone domain-containing protein.
 
 
 0.890
HIST1H3E
Histone H3; Belongs to the histone H3 family.
 
 
 0.861
H2AX
Histone H2A; Belongs to the histone H2A family.
 
 0.839
LOC100521680
Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...]
 
 
 0.836
CENPA
Centromere protein A.
   
 0.832
H2AJ
Histone H2A; Belongs to the histone H2A family.
 
 0.813
F1RWC9_PIG
Histone domain-containing protein.
 
 
 0.804
H2AC20
Histone H2A; Belongs to the histone H2A family.
 
 0.777
F2Z5K9_PIG
Histone domain-containing protein.
 
 
 
 0.776
H2AC1
Histone H2A; Belongs to the histone H2A family.
 
 0.776
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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