SLA-6 protein (Sus scrofa) - STRING interaction network

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Score

SLA-6

Ig-like domain-containing protein; Belongs to the MHC class I family. (462 aa)

Predicted Functional Partners:

B2M

0.936

CD8A

0.919

CALR

0.866

PDIA3

0.852

TAP1

0.847

CD8B

0.847

SLA-DMA

0.820

KLRD1

0.795

HLA-DRA

0.745

A0A287BQ31_PIG

0.706

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A287BQ31_PIG	B2M	ENSSSCP00000058284	ENSSSCP00000050390	Ig-like domain-containing protein.	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	0.500
A0A287BQ31_PIG	CD8A	ENSSSCP00000058284	ENSSSCP00000040606	Ig-like domain-containing protein.	CD8a molecule.	0.534
A0A287BQ31_PIG	CD8B	ENSSSCP00000058284	ENSSSCP00000008768	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.599
A0A287BQ31_PIG	HLA-DRA	ENSSSCP00000058284	ENSSSCP00000001567	Ig-like domain-containing protein.	Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family.	0.882
A0A287BQ31_PIG	SLA-6	ENSSSCP00000058284	ENSSSCP00000001485	Ig-like domain-containing protein.	Ig-like domain-containing protein; Belongs to the MHC class I family.	0.706
B2M	A0A287BQ31_PIG	ENSSSCP00000050390	ENSSSCP00000058284	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	Ig-like domain-containing protein.	0.500
B2M	CALR	ENSSSCP00000050390	ENSSSCP00000014615	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	Calreticulin; Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (By similarity). Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis; Belongs to the calreticulin family.	0.839
B2M	CD8A	ENSSSCP00000050390	ENSSSCP00000040606	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	CD8a molecule.	0.912
B2M	CD8B	ENSSSCP00000050390	ENSSSCP00000008768	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	Ig-like domain-containing protein.	0.747
B2M	HLA-DRA	ENSSSCP00000050390	ENSSSCP00000001567	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family.	0.932
B2M	KLRD1	ENSSSCP00000050390	ENSSSCP00000074449	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	Killer cell lectin like receptor D1.	0.787
B2M	PDIA3	ENSSSCP00000050390	ENSSSCP00000005064	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	Protein disulfide-isomerase.	0.915
B2M	SLA-6	ENSSSCP00000050390	ENSSSCP00000001485	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	Ig-like domain-containing protein; Belongs to the MHC class I family.	0.936
B2M	SLA-DMA	ENSSSCP00000050390	ENSSSCP00000030928	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	Ig-like domain-containing protein; Belongs to the MHC class II family.	0.553
B2M	TAP1	ENSSSCP00000050390	ENSSSCP00000001588	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	Transporter 1, ATP binding cassette subfamily B member.	0.863
CALR	B2M	ENSSSCP00000014615	ENSSSCP00000050390	Calreticulin; Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (By similarity). Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis; Belongs to the calreticulin family.	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	0.839
CALR	CD8A	ENSSSCP00000014615	ENSSSCP00000040606	Calreticulin; Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (By similarity). Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis; Belongs to the calreticulin family.	CD8a molecule.	0.639
CALR	PDIA3	ENSSSCP00000014615	ENSSSCP00000005064	Calreticulin; Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (By similarity). Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis; Belongs to the calreticulin family.	Protein disulfide-isomerase.	0.999
CALR	SLA-6	ENSSSCP00000014615	ENSSSCP00000001485	Calreticulin; Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (By similarity). Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis; Belongs to the calreticulin family.	Ig-like domain-containing protein; Belongs to the MHC class I family.	0.866
CALR	TAP1	ENSSSCP00000014615	ENSSSCP00000001588	Calreticulin; Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (By similarity). Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis; Belongs to the calreticulin family.	Transporter 1, ATP binding cassette subfamily B member.	0.984