node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C1QA | C1QB | ENSSSCP00000058150 | ENSSSCP00000063693 | Complement C1q subcomponent subunit A; C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. | Complement C1q B chain. | 0.998 |
C1QA | C1QC | ENSSSCP00000058150 | ENSSSCP00000034440 | Complement C1q subcomponent subunit A; C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. | Complement C1q subcomponent subunit C isoform 1. | 0.999 |
C1QA | C2 | ENSSSCP00000058150 | ENSSSCP00000001521 | Complement C1q subcomponent subunit A; C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. | Uncharacterized protein; Belongs to the peptidase S1 family. | 0.924 |
C1QA | C3 | ENSSSCP00000058150 | ENSSSCP00000014399 | Complement C1q subcomponent subunit A; C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. | Complement C3c alpha' chain fragment 1; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates (By similarity). [C3-beta-c]: Acts as a chemoattractant for neutrophils in chronic inflammation. | 0.426 |
C1QA | C4A | ENSSSCP00000058150 | ENSSSCP00000061845 | Complement C1q subcomponent subunit A; C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. | Uncharacterized protein. | 0.936 |
C1QA | MASP1 | ENSSSCP00000058150 | ENSSSCP00000062448 | Complement C1q subcomponent subunit A; C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. | Mannan-binding lectin serine protease 1 isoform 2; Belongs to the peptidase S1 family. | 0.614 |
C1QA | MASP2 | ENSSSCP00000058150 | ENSSSCP00000028476 | Complement C1q subcomponent subunit A; C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. | Uncharacterized protein; Belongs to the peptidase S1 family. | 0.711 |
C1QB | C1QA | ENSSSCP00000063693 | ENSSSCP00000058150 | Complement C1q B chain. | Complement C1q subcomponent subunit A; C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. | 0.998 |
C1QB | C1QC | ENSSSCP00000063693 | ENSSSCP00000034440 | Complement C1q B chain. | Complement C1q subcomponent subunit C isoform 1. | 0.998 |
C1QB | C2 | ENSSSCP00000063693 | ENSSSCP00000001521 | Complement C1q B chain. | Uncharacterized protein; Belongs to the peptidase S1 family. | 0.937 |
C1QB | C3 | ENSSSCP00000063693 | ENSSSCP00000014399 | Complement C1q B chain. | Complement C3c alpha' chain fragment 1; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates (By similarity). [C3-beta-c]: Acts as a chemoattractant for neutrophils in chronic inflammation. | 0.457 |
C1QB | C4A | ENSSSCP00000063693 | ENSSSCP00000061845 | Complement C1q B chain. | Uncharacterized protein. | 0.930 |
C1QB | MASP1 | ENSSSCP00000063693 | ENSSSCP00000062448 | Complement C1q B chain. | Mannan-binding lectin serine protease 1 isoform 2; Belongs to the peptidase S1 family. | 0.490 |
C1QB | MASP2 | ENSSSCP00000063693 | ENSSSCP00000028476 | Complement C1q B chain. | Uncharacterized protein; Belongs to the peptidase S1 family. | 0.641 |
C1QC | C1QA | ENSSSCP00000034440 | ENSSSCP00000058150 | Complement C1q subcomponent subunit C isoform 1. | Complement C1q subcomponent subunit A; C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. | 0.999 |
C1QC | C1QB | ENSSSCP00000034440 | ENSSSCP00000063693 | Complement C1q subcomponent subunit C isoform 1. | Complement C1q B chain. | 0.998 |
C1QC | C2 | ENSSSCP00000034440 | ENSSSCP00000001521 | Complement C1q subcomponent subunit C isoform 1. | Uncharacterized protein; Belongs to the peptidase S1 family. | 0.910 |
C1QC | C3 | ENSSSCP00000034440 | ENSSSCP00000014399 | Complement C1q subcomponent subunit C isoform 1. | Complement C3c alpha' chain fragment 1; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates (By similarity). [C3-beta-c]: Acts as a chemoattractant for neutrophils in chronic inflammation. | 0.483 |
C1QC | C4A | ENSSSCP00000034440 | ENSSSCP00000061845 | Complement C1q subcomponent subunit C isoform 1. | Uncharacterized protein. | 0.914 |
C1QC | MASP1 | ENSSSCP00000034440 | ENSSSCP00000062448 | Complement C1q subcomponent subunit C isoform 1. | Mannan-binding lectin serine protease 1 isoform 2; Belongs to the peptidase S1 family. | 0.507 |