NOTCH4 protein (Sus scrofa) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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Textmining

[Homology]

Score

NOTCH4

Uncharacterized protein. (1993 aa)

Predicted Functional Partners:

JAG1

0.994

JAG2

0.993

DLL4

0.993

DLL3

0.988

DLL1

0.985

RBPJ

0.964

NUMB

0.946

LFNG

0.942

MFNG

0.934

MAML1

0.930

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DLL1	DLL3	ENSSSCP00000025758	ENSSSCP00000066353	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta like canonical Notch ligand 3.	0.917
DLL1	DLL4	ENSSSCP00000025758	ENSSSCP00000055160	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.914
DLL1	LFNG	ENSSSCP00000025758	ENSSSCP00000008089	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Beta-1,3-N-acetylglucosaminyltransferase.	0.610
DLL1	MAML1	ENSSSCP00000025758	ENSSSCP00000014906	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Mastermind like transcriptional coactivator 1.	0.710
DLL1	MFNG	ENSSSCP00000025758	ENSSSCP00000021102	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Beta-1,3-N-acetylglucosaminyltransferase.	0.546
DLL1	NOTCH4	ENSSSCP00000025758	ENSSSCP00000001551	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.985
DLL1	NUMB	ENSSSCP00000025758	ENSSSCP00000040817	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	NUMB endocytic adaptor protein.	0.503
DLL1	RBPJ	ENSSSCP00000025758	ENSSSCP00000038442	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Recombination signal binding protein for immunoglobulin kappa J region.	0.787
DLL3	DLL1	ENSSSCP00000066353	ENSSSCP00000025758	Delta like canonical Notch ligand 3.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.917
DLL3	DLL4	ENSSSCP00000066353	ENSSSCP00000055160	Delta like canonical Notch ligand 3.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.923
DLL3	LFNG	ENSSSCP00000066353	ENSSSCP00000008089	Delta like canonical Notch ligand 3.	Beta-1,3-N-acetylglucosaminyltransferase.	0.488
DLL3	MAML1	ENSSSCP00000066353	ENSSSCP00000014906	Delta like canonical Notch ligand 3.	Mastermind like transcriptional coactivator 1.	0.622
DLL3	NOTCH4	ENSSSCP00000066353	ENSSSCP00000001551	Delta like canonical Notch ligand 3.	Uncharacterized protein.	0.988
DLL3	NUMB	ENSSSCP00000066353	ENSSSCP00000040817	Delta like canonical Notch ligand 3.	NUMB endocytic adaptor protein.	0.422
DLL3	RBPJ	ENSSSCP00000066353	ENSSSCP00000038442	Delta like canonical Notch ligand 3.	Recombination signal binding protein for immunoglobulin kappa J region.	0.659
DLL4	DLL1	ENSSSCP00000055160	ENSSSCP00000025758	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.914
DLL4	DLL3	ENSSSCP00000055160	ENSSSCP00000066353	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta like canonical Notch ligand 3.	0.923
DLL4	JAG2	ENSSSCP00000055160	ENSSSCP00000028498	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.463
DLL4	LFNG	ENSSSCP00000055160	ENSSSCP00000008089	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Beta-1,3-N-acetylglucosaminyltransferase.	0.641
DLL4	MAML1	ENSSSCP00000055160	ENSSSCP00000014906	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Mastermind like transcriptional coactivator 1.	0.662