SLA-DMB protein (Sus scrofa) - STRING interaction network

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Score

SLA-DMB

Major histocompatibility complex, class II, DM beta. (272 aa)

Predicted Functional Partners:

SLA-DMA

0.999

HLA-DRA

0.998

CD74

0.982

SLA-DQA1

0.962

HLA-DOB

0.954

SLA-DOA

0.933

CD4

0.907

CD247

0.890

SLA-DQB1

0.871

SLA-DRB1

0.868

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD247	CD4	ENSSSCP00000030740	ENSSSCP00000019155	T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of d [...]	CD4 molecule.	0.829
CD247	HLA-DOB	ENSSSCP00000030740	ENSSSCP00000001577	T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of d [...]	HLA class II histocompatibility antigen, DO beta chain.	0.897
CD247	HLA-DRA	ENSSSCP00000030740	ENSSSCP00000001567	T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of d [...]	Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family.	0.948
CD247	SLA-DMA	ENSSSCP00000030740	ENSSSCP00000030928	T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of d [...]	Ig-like domain-containing protein; Belongs to the MHC class II family.	0.890
CD247	SLA-DMB	ENSSSCP00000030740	ENSSSCP00000001591	T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of d [...]	Major histocompatibility complex, class II, DM beta.	0.890
CD247	SLA-DOA	ENSSSCP00000030740	ENSSSCP00000001596	T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of d [...]	Ig-like domain-containing protein; Belongs to the MHC class II family.	0.755
CD247	SLA-DQA1	ENSSSCP00000030740	ENSSSCP00000070034	T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of d [...]	SLA class II histocompatibility antigen, DQ haplotype D alpha chain.	0.938
CD247	SLA-DRB1	ENSSSCP00000030740	ENSSSCP00000055121	T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of d [...]	Ig-like domain-containing protein.	0.820
CD4	CD247	ENSSSCP00000019155	ENSSSCP00000030740	CD4 molecule.	T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of d [...]	0.829
CD4	CD74	ENSSSCP00000019155	ENSSSCP00000050395	CD4 molecule.	Thyroglobulin type-1 domain-containing protein.	0.543
CD4	HLA-DOB	ENSSSCP00000019155	ENSSSCP00000001577	CD4 molecule.	HLA class II histocompatibility antigen, DO beta chain.	0.842
CD4	HLA-DRA	ENSSSCP00000019155	ENSSSCP00000001567	CD4 molecule.	Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family.	0.993
CD4	SLA-DMA	ENSSSCP00000019155	ENSSSCP00000030928	CD4 molecule.	Ig-like domain-containing protein; Belongs to the MHC class II family.	0.911
CD4	SLA-DMB	ENSSSCP00000019155	ENSSSCP00000001591	CD4 molecule.	Major histocompatibility complex, class II, DM beta.	0.907
CD4	SLA-DOA	ENSSSCP00000019155	ENSSSCP00000001596	CD4 molecule.	Ig-like domain-containing protein; Belongs to the MHC class II family.	0.815
CD4	SLA-DQA1	ENSSSCP00000019155	ENSSSCP00000070034	CD4 molecule.	SLA class II histocompatibility antigen, DQ haplotype D alpha chain.	0.949
CD4	SLA-DRB1	ENSSSCP00000019155	ENSSSCP00000055121	CD4 molecule.	Ig-like domain-containing protein.	0.855
CD74	CD4	ENSSSCP00000050395	ENSSSCP00000019155	Thyroglobulin type-1 domain-containing protein.	CD4 molecule.	0.543
CD74	HLA-DOB	ENSSSCP00000050395	ENSSSCP00000001577	Thyroglobulin type-1 domain-containing protein.	HLA class II histocompatibility antigen, DO beta chain.	0.988
CD74	HLA-DRA	ENSSSCP00000050395	ENSSSCP00000001567	Thyroglobulin type-1 domain-containing protein.	Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family.	0.999