HMGCLL1 protein (Sus scrofa) - STRING interaction network

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Predicted Interactions

gene neighborhood

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Score

HMGCLL1

3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. (425 aa)

Predicted Functional Partners:

HMGCS1

0.976

HMGCS2

0.976

AUH

0.966

OXCT1

0.964

ACAT2

0.962

BDH1

0.960

ACAT1

0.950

AACS

0.948

ACAA1

0.940

ACAA2

0.935

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AACS	ACAA1	ENSSSCP00000010417	ENSSSCP00000011995	Acetoacetyl-CoA synthetase.	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.504
AACS	ACAA2	ENSSSCP00000010417	ENSSSCP00000004865	Acetoacetyl-CoA synthetase.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.609
AACS	ACAT1	ENSSSCP00000010417	ENSSSCP00000025827	Acetoacetyl-CoA synthetase.	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.960
AACS	ACAT2	ENSSSCP00000010417	ENSSSCP00000047700	Acetoacetyl-CoA synthetase.	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	0.963
AACS	AUH	ENSSSCP00000010417	ENSSSCP00000010238	Acetoacetyl-CoA synthetase.	Methylglutaconyl-CoA hydratase, mitochondrial isoform X1; Belongs to the enoyl-CoA hydratase/isomerase family.	0.407
AACS	BDH1	ENSSSCP00000010417	ENSSSCP00000012603	Acetoacetyl-CoA synthetase.	D-beta-hydroxybutyrate dehydrogenase, mitochondrial; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.944
AACS	HMGCLL1	ENSSSCP00000010417	ENSSSCP00000001608	Acetoacetyl-CoA synthetase.	3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1.	0.948
AACS	HMGCS1	ENSSSCP00000010417	ENSSSCP00000017880	Acetoacetyl-CoA synthetase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.951
AACS	HMGCS2	ENSSSCP00000010417	ENSSSCP00000034427	Acetoacetyl-CoA synthetase.	Hydroxymethylglutaryl-CoA synthase, mitochondrial; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase; Belongs to the thiolase-like superfamily. HMG-CoA synthase family.	0.952
AACS	OXCT1	ENSSSCP00000010417	ENSSSCP00000068644	Acetoacetyl-CoA synthetase.	Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.923
ACAA1	AACS	ENSSSCP00000011995	ENSSSCP00000010417	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acetoacetyl-CoA synthetase.	0.504
ACAA1	ACAA2	ENSSSCP00000011995	ENSSSCP00000004865	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.931
ACAA1	ACAT1	ENSSSCP00000011995	ENSSSCP00000025827	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.944
ACAA1	ACAT2	ENSSSCP00000011995	ENSSSCP00000047700	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	0.920
ACAA1	AUH	ENSSSCP00000011995	ENSSSCP00000010238	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Methylglutaconyl-CoA hydratase, mitochondrial isoform X1; Belongs to the enoyl-CoA hydratase/isomerase family.	0.741
ACAA1	HMGCLL1	ENSSSCP00000011995	ENSSSCP00000001608	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1.	0.940
ACAA1	HMGCS1	ENSSSCP00000011995	ENSSSCP00000017880	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.987
ACAA1	HMGCS2	ENSSSCP00000011995	ENSSSCP00000034427	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Hydroxymethylglutaryl-CoA synthase, mitochondrial; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase; Belongs to the thiolase-like superfamily. HMG-CoA synthase family.	0.987
ACAA1	OXCT1	ENSSSCP00000011995	ENSSSCP00000068644	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.936
ACAA2	AACS	ENSSSCP00000004865	ENSSSCP00000010417	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Acetoacetyl-CoA synthetase.	0.609