GCLC protein (Sus scrofa) - STRING interaction network

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Score

GCLC

Glutamate--cysteine ligase catalytic subunit isoform X3. (588 aa)

Predicted Functional Partners:

GCLM

0.999

GSS

0.989

OPLAH

0.951

GGT6

0.950

GGT7

0.936

GGT1

0.929

GGCT

0.907

AGXT2

0.903

BCAT2

0.900

LAP3

0.900

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGXT2	BCAT2	ENSSSCP00000034701	ENSSSCP00000003396	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Branched-chain-amino-acid aminotransferase, mitochondrial; Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids (By similarity).	0.932
AGXT2	GCLC	ENSSSCP00000034701	ENSSSCP00000001618	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Glutamate--cysteine ligase catalytic subunit isoform X3.	0.903
AGXT2	GCLM	ENSSSCP00000034701	ENSSSCP00000040673	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Glutamate--cysteine ligase regulatory subunit.	0.903
BCAT2	AGXT2	ENSSSCP00000003396	ENSSSCP00000034701	Branched-chain-amino-acid aminotransferase, mitochondrial; Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids (By similarity).	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.932
BCAT2	GCLC	ENSSSCP00000003396	ENSSSCP00000001618	Branched-chain-amino-acid aminotransferase, mitochondrial; Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids (By similarity).	Glutamate--cysteine ligase catalytic subunit isoform X3.	0.900
BCAT2	GCLM	ENSSSCP00000003396	ENSSSCP00000040673	Branched-chain-amino-acid aminotransferase, mitochondrial; Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids (By similarity).	Glutamate--cysteine ligase regulatory subunit.	0.907
GCLC	AGXT2	ENSSSCP00000001618	ENSSSCP00000034701	Glutamate--cysteine ligase catalytic subunit isoform X3.	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.903
GCLC	BCAT2	ENSSSCP00000001618	ENSSSCP00000003396	Glutamate--cysteine ligase catalytic subunit isoform X3.	Branched-chain-amino-acid aminotransferase, mitochondrial; Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids (By similarity).	0.900
GCLC	GCLM	ENSSSCP00000001618	ENSSSCP00000040673	Glutamate--cysteine ligase catalytic subunit isoform X3.	Glutamate--cysteine ligase regulatory subunit.	0.999
GCLC	GGCT	ENSSSCP00000001618	ENSSSCP00000073129	Glutamate--cysteine ligase catalytic subunit isoform X3.	Uncharacterized protein.	0.907
GCLC	GGT1	ENSSSCP00000001618	ENSSSCP00000030498	Glutamate--cysteine ligase catalytic subunit isoform X3.	Glutathione hydrolase 1 heavy chain; Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly), glutathione conjugates, and other gamma-glutamyl compounds. The metabolism of glutathione releases free glutamate and the dipeptide cysteinyl-glycine, which is hydrolyzed to cysteine and glycine by dipeptidases. In the presence of high concentrations of dipeptides and some amino acids, can also catalyze a transpeptidation reaction, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound. Initiates extracellular glutathione [...]	0.929
GCLC	GGT6	ENSSSCP00000001618	ENSSSCP00000018943	Glutamate--cysteine ligase catalytic subunit isoform X3.	Gamma-glutamyltransferase 6.	0.950
GCLC	GGT7	ENSSSCP00000001618	ENSSSCP00000007757	Glutamate--cysteine ligase catalytic subunit isoform X3.	Gamma-glutamyltransferase 7.	0.936
GCLC	GSS	ENSSSCP00000001618	ENSSSCP00000034338	Glutamate--cysteine ligase catalytic subunit isoform X3.	Glutathione synthetase.	0.989
GCLC	LAP3	ENSSSCP00000001618	ENSSSCP00000061377	Glutamate--cysteine ligase catalytic subunit isoform X3.	Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides; Belongs to the peptidase M17 family.	0.900
GCLC	OPLAH	ENSSSCP00000001618	ENSSSCP00000006320	Glutamate--cysteine ligase catalytic subunit isoform X3.	5-oxoprolinase, ATP-hydrolysing.	0.951
GCLM	AGXT2	ENSSSCP00000040673	ENSSSCP00000034701	Glutamate--cysteine ligase regulatory subunit.	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.903
GCLM	BCAT2	ENSSSCP00000040673	ENSSSCP00000003396	Glutamate--cysteine ligase regulatory subunit.	Branched-chain-amino-acid aminotransferase, mitochondrial; Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids (By similarity).	0.907
GCLM	GCLC	ENSSSCP00000040673	ENSSSCP00000001618	Glutamate--cysteine ligase regulatory subunit.	Glutamate--cysteine ligase catalytic subunit isoform X3.	0.999
GCLM	GGCT	ENSSSCP00000040673	ENSSSCP00000073129	Glutamate--cysteine ligase regulatory subunit.	Uncharacterized protein.	0.909