Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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[Homology]
Score
B3GALT4Hexosyltransferase. (377 aa)    
Predicted Functional Partners:
ST3GAL1
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1; Responsible for the synthesis of the sequence NeuAc-alpha- 2,3-Gal-beta-1,3-GalNAc- found on sugar chains O-linked to Thr or Ser and also as a terminal sequence on certain gangliosides. SIAT4A and SIAT4B sialylate the same acceptor substrates but exhibit different Km values. The short isoform seems to be catalytically inactive. Belongs to the glycosyltransferase 29 family.
     
 0.962
ST3GAL2
ST3 beta-galactoside alpha-2,3-sialyltransferase 2; Belongs to the glycosyltransferase 29 family.
     
 0.962
HEXA
Beta-hexosaminidase.
     
 0.948
PGAP4
Transmembrane protein 246.
     
 0.931
HEXB
Beta-hexosaminidase subunit beta; Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues.
     
 0.929
GLB1
Beta-galactosidase.
     
 0.919
B4GALNT1
Beta-1,4 N-acetylgalactosaminyltransferase 1 isoform X5.
     
 0.885
SULT6B1
Sulfotransferase; Belongs to the sulfotransferase 1 family.
      
 0.826
A4GALT
Lactosylceramide 4-alpha-galactosyltransferase isoform X1.
   
 
 0.747
FRMD1
FERM domain-containing protein.
   
  
 0.704
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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