Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PFDN6Prefoldin subunit 6. (129 aa)    
Predicted Functional Partners:
PFDN2
Prefoldin subunit 2.
   
 0.999
PFDN4
Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family.
   
 0.999
PFDN1
Prefoldin subunit 1.
   
 0.999
VBP1
Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family.
   
 0.998
PFDN5
Prefoldin subunit 5.
   
 0.996
RPAP3
RNA polymerase II associated protein 3.
   
 
 0.967
URI1
URI1 prefoldin like chaperone.
    
 
 0.947
PDRG1
P53 and DNA damage regulated 1.
    
 0.935
UXT
Ubiquitously expressed prefoldin like chaperone.
    
 
 0.933
CCT4
T-complex protein 1 subunit delta.
   
 
 0.818
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
Server load: low (10%) [HD]