Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ARMC12Armadillo repeat containing 12. (363 aa)    
Predicted Functional Partners:
TBC1D21
TBC1 domain family member 21.
   
  
 0.853
FCSK
Fucose kinase.
      
 0.707
COG4
Conserved oligomeric Golgi complex subunit 4 isoform 1.
      
 0.703
CIB3
Calcium and integrin binding family member 3.
    
 
 0.702
DMRTA1
Doublesex-and mab-3-related transcription factor A1.
      
 0.680
TRIM7
Tripartite motif containing 7.
    
 
 0.621
CASS4
Cas scaffolding protein family member 4; Docking protein that plays a role in tyrosine kinase-based signaling related to cell adhesion and cell spreading. Regulates PTK2/FAK1 activity, focal adhesion integrity, and cell spreading (By similarity).
   
  
 0.602
IGFBP4
Insulin-like growth factor-binding protein 4; IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
      
 0.593
VDAC3
Voltage-dependent anion-selective channel protein 3; Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules; Belongs to the eukaryotic mitochondrial porin family.
      
 0.580
ARMC1
Armadillo repeat-containing protein 1.
      
 0.556
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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