CLPS protein (Sus scrofa) - STRING interaction network

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CLPS

Colipase; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase. (112 aa)

Predicted Functional Partners:

PNLIP

0.994

PNLIPRP3

0.949

PNLIPRP2

0.949

PLA2G1B

0.945

PNLIPRP1

0.944

CEL

0.938

CTRL

0.835

LOC100739735

0.818

LOC100621820

0.794

LOC110261434

0.788

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CEL	CLPS	ENSSSCP00000027456	ENSSSCP00000001686	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Colipase; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.	0.938
CEL	CTRL	ENSSSCP00000027456	ENSSSCP00000021733	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Chymotrypsin like; Belongs to the peptidase S1 family.	0.981
CEL	LOC100621820	ENSSSCP00000027456	ENSSSCP00000023533	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.917
CEL	LOC100739735	ENSSSCP00000027456	ENSSSCP00000051113	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.917
CEL	LOC110261434	ENSSSCP00000027456	ENSSSCP00000054486	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.979
CEL	PLA2G1B	ENSSSCP00000027456	ENSSSCP00000072242	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Phospholipase A2, major isoenzyme; PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides, this releases glycerophospholipids and arachidonic acid that serve as the precursors of signal molecules. Belongs to the phospholipase A2 family.	0.718
CEL	PNLIP	ENSSSCP00000027456	ENSSSCP00000011355	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Pancreatic triacylglycerol lipase.	0.980
CEL	PNLIPRP1	ENSSSCP00000027456	ENSSSCP00000011357	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.979
CEL	PNLIPRP2	ENSSSCP00000027456	ENSSSCP00000050863	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.981
CEL	PNLIPRP3	ENSSSCP00000027456	ENSSSCP00000011354	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.977
CLPS	CEL	ENSSSCP00000001686	ENSSSCP00000027456	Colipase; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.938
CLPS	CTRL	ENSSSCP00000001686	ENSSSCP00000021733	Colipase; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.	Chymotrypsin like; Belongs to the peptidase S1 family.	0.835
CLPS	LOC100621820	ENSSSCP00000001686	ENSSSCP00000023533	Colipase; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.794
CLPS	LOC100739735	ENSSSCP00000001686	ENSSSCP00000051113	Colipase; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.818
CLPS	LOC110261434	ENSSSCP00000001686	ENSSSCP00000054486	Colipase; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.788
CLPS	PLA2G1B	ENSSSCP00000001686	ENSSSCP00000072242	Colipase; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.	Phospholipase A2, major isoenzyme; PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides, this releases glycerophospholipids and arachidonic acid that serve as the precursors of signal molecules. Belongs to the phospholipase A2 family.	0.945
CLPS	PNLIP	ENSSSCP00000001686	ENSSSCP00000011355	Colipase; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.	Pancreatic triacylglycerol lipase.	0.994
CLPS	PNLIPRP1	ENSSSCP00000001686	ENSSSCP00000011357	Colipase; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.944
CLPS	PNLIPRP2	ENSSSCP00000001686	ENSSSCP00000050863	Colipase; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.949
CLPS	PNLIPRP3	ENSSSCP00000001686	ENSSSCP00000011354	Colipase; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.949

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