STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIM1Pim-1 proto-oncogene, serine/threonine kinase. (518 aa)    
Predicted Functional Partners:
PIM2
Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
  
  
 
0.902
NUMA1
Nuclear mitotic apparatus protein 1.
    
 
 0.706
DDX6
Putative ATP-dependent RNA helicase DDX6 isoform X1; Belongs to the DEAD box helicase family.
   
 
 0.631
S100A14
Protein S100-A14 isoform X1; Belongs to the S-100 family.
      
 0.607
EDC3
Enhancer of mRNA decapping 3.
   
 
 0.584
DCP1A
mRNA-decapping enzyme 1A; Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1; Belongs to the DCP1 family.
    
 
 0.582
DCP1B
Decapping mRNA 1B.
    
 
 0.559
RNPS1
RNA binding protein with serine rich domain 1.
    
 
 0.555
MYBL1
Myb-related protein A isoform 1.
      
 0.512
DNAJB6
DnaJ heat shock protein family (Hsp40) member B6.
   
 
 0.484
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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