MDGA1 protein (Sus scrofa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

MDGA1

MAM domain-containing glycosylphosphatidylinositol anchor protein 1 preproprotein. (955 aa)

Predicted Functional Partners:

SYT6

0.845

NLGN3

0.785

MN1

0.778

PCP4

0.723

NLGN1

0.635

LRFN5

0.614

CACNA1H

0.597

HACD4

0.577

LOC100624109

0.567

LOC100624109-2

0.567

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CACNA1H	MDGA1	ENSSSCP00000031360	ENSSSCP00000001716	Voltage-dependent T-type calcium channel subunit alpha-1H isoform a.	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 preproprotein.	0.597
CACNA1H	PCP4	ENSSSCP00000031360	ENSSSCP00000031224	Voltage-dependent T-type calcium channel subunit alpha-1H isoform a.	Purkinje cell protein 4.	0.552
CACNA1H	SYT6	ENSSSCP00000031360	ENSSSCP00000040684	Voltage-dependent T-type calcium channel subunit alpha-1H isoform a.	Synaptotagmin 6.	0.689
HACD4	MDGA1	ENSSSCP00000040121	ENSSSCP00000001716	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 preproprotein.	0.577
LOC100624109	LOC100624109-2	ENSSSCP00000033441	ENSSSCP00000042302	COesterase domain-containing protein.	COesterase domain-containing protein.	0.801
LOC100624109	MDGA1	ENSSSCP00000033441	ENSSSCP00000001716	COesterase domain-containing protein.	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 preproprotein.	0.567
LOC100624109	NLGN1	ENSSSCP00000033441	ENSSSCP00000012527	COesterase domain-containing protein.	Neuroligin 1.	0.506
LOC100624109	NLGN3	ENSSSCP00000033441	ENSSSCP00000040532	COesterase domain-containing protein.	Neuroligin-3 isoform 1.	0.592
LOC100624109-2	LOC100624109	ENSSSCP00000042302	ENSSSCP00000033441	COesterase domain-containing protein.	COesterase domain-containing protein.	0.801
LOC100624109-2	MDGA1	ENSSSCP00000042302	ENSSSCP00000001716	COesterase domain-containing protein.	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 preproprotein.	0.567
LOC100624109-2	NLGN1	ENSSSCP00000042302	ENSSSCP00000012527	COesterase domain-containing protein.	Neuroligin 1.	0.901
LOC100624109-2	NLGN3	ENSSSCP00000042302	ENSSSCP00000040532	COesterase domain-containing protein.	Neuroligin-3 isoform 1.	0.918
LRFN5	MDGA1	ENSSSCP00000005367	ENSSSCP00000001716	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 isoform X1.	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 preproprotein.	0.614
MDGA1	CACNA1H	ENSSSCP00000001716	ENSSSCP00000031360	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 preproprotein.	Voltage-dependent T-type calcium channel subunit alpha-1H isoform a.	0.597
MDGA1	HACD4	ENSSSCP00000001716	ENSSSCP00000040121	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 preproprotein.	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	0.577
MDGA1	LOC100624109	ENSSSCP00000001716	ENSSSCP00000033441	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 preproprotein.	COesterase domain-containing protein.	0.567
MDGA1	LOC100624109-2	ENSSSCP00000001716	ENSSSCP00000042302	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 preproprotein.	COesterase domain-containing protein.	0.567
MDGA1	LRFN5	ENSSSCP00000001716	ENSSSCP00000005367	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 preproprotein.	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 isoform X1.	0.614
MDGA1	MN1	ENSSSCP00000001716	ENSSSCP00000010637	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 preproprotein.	MN1 proto-oncogene, transcriptional regulator.	0.778
MDGA1	NLGN1	ENSSSCP00000001716	ENSSSCP00000012527	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 preproprotein.	Neuroligin 1.	0.635