Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
KCNK17Potassium two pore domain channel subfamily K member 17; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (326 aa)    
Predicted Functional Partners:
CFAP100
Cilia and flagella associated protein 100.
      
 0.871
MARCHF10
Membrane associated ring-CH-type finger 10.
      
 0.827
CCDC189
Coiled-coil domain-containing protein 189 isoform X1.
      
 0.821
KIF24
Kinesin family member 24; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
  
 0.739
KCNK16
Potassium two pore domain channel subfamily K member 16; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
  
  
0.729
HIPK4
Homeodomain-interacting protein kinase 4.
      
 0.725
KCNK3
Potassium channel subfamily K member.
   
 
0.647
KCNK9
Potassium channel subfamily K member.
   
 
0.647
SCN10A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
      
 0.646
PLA2G3
Phospholipase A2 group III.
      
 0.645
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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