TFEB protein (Sus scrofa) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

TFEB

Transcription factor EB. (451 aa)

Predicted Functional Partners:

YWHAB

0.972

MTOR

0.900

LAMP1

0.883

MCOLN1

0.852

CTSD

0.834

RPTOR

0.800

RRAGC

0.768

ATG13

0.745

BECN1

0.738

RRAGA

0.730

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG13	BECN1	ENSSSCP00000014089	ENSSSCP00000018420	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily.	Beclin-1-C 35 kDa; Plays a central role in autophagy. Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3- phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex f [...]	0.928
ATG13	LAMP1	ENSSSCP00000014089	ENSSSCP00000010202	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily.	Uncharacterized protein.	0.473
ATG13	MTOR	ENSSSCP00000014089	ENSSSCP00000003699	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.955
ATG13	RPTOR	ENSSSCP00000014089	ENSSSCP00000020553	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily.	Regulatory associated protein of MTOR complex 1.	0.966
ATG13	RRAGA	ENSSSCP00000014089	ENSSSCP00000005562	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily.	Ras related GTP binding A.	0.582
ATG13	RRAGC	ENSSSCP00000014089	ENSSSCP00000003953	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily.	Ras related GTP binding C.	0.563
ATG13	TFEB	ENSSSCP00000014089	ENSSSCP00000001762	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily.	Transcription factor EB.	0.745
BECN1	ATG13	ENSSSCP00000018420	ENSSSCP00000014089	Beclin-1-C 35 kDa; Plays a central role in autophagy. Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3- phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex f [...]	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily.	0.928
BECN1	CTSD	ENSSSCP00000018420	ENSSSCP00000036066	Beclin-1-C 35 kDa; Plays a central role in autophagy. Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3- phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex f [...]	Cathepsin D heavy chain; Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation; Belongs to the peptidase A1 family.	0.629
BECN1	LAMP1	ENSSSCP00000018420	ENSSSCP00000010202	Beclin-1-C 35 kDa; Plays a central role in autophagy. Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3- phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex f [...]	Uncharacterized protein.	0.858
BECN1	MCOLN1	ENSSSCP00000018420	ENSSSCP00000037558	Beclin-1-C 35 kDa; Plays a central role in autophagy. Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3- phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex f [...]	Mucolipin 1.	0.586
BECN1	MTOR	ENSSSCP00000018420	ENSSSCP00000003699	Beclin-1-C 35 kDa; Plays a central role in autophagy. Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3- phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex f [...]	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.756
BECN1	RPTOR	ENSSSCP00000018420	ENSSSCP00000020553	Beclin-1-C 35 kDa; Plays a central role in autophagy. Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3- phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex f [...]	Regulatory associated protein of MTOR complex 1.	0.409
BECN1	TFEB	ENSSSCP00000018420	ENSSSCP00000001762	Beclin-1-C 35 kDa; Plays a central role in autophagy. Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3- phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex f [...]	Transcription factor EB.	0.738
CTSD	BECN1	ENSSSCP00000036066	ENSSSCP00000018420	Cathepsin D heavy chain; Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation; Belongs to the peptidase A1 family.	Beclin-1-C 35 kDa; Plays a central role in autophagy. Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3- phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex f [...]	0.629
CTSD	LAMP1	ENSSSCP00000036066	ENSSSCP00000010202	Cathepsin D heavy chain; Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation; Belongs to the peptidase A1 family.	Uncharacterized protein.	0.967
CTSD	MCOLN1	ENSSSCP00000036066	ENSSSCP00000037558	Cathepsin D heavy chain; Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation; Belongs to the peptidase A1 family.	Mucolipin 1.	0.558
CTSD	TFEB	ENSSSCP00000036066	ENSSSCP00000001762	Cathepsin D heavy chain; Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation; Belongs to the peptidase A1 family.	Transcription factor EB.	0.834
LAMP1	ATG13	ENSSSCP00000010202	ENSSSCP00000014089	Uncharacterized protein.	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily.	0.473
LAMP1	BECN1	ENSSSCP00000010202	ENSSSCP00000018420	Uncharacterized protein.	Beclin-1-C 35 kDa; Plays a central role in autophagy. Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3- phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex f [...]	0.858