STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GUCA1AUncharacterized protein. (205 aa)    
Predicted Functional Partners:
GUCA1B
Guanylate cyclase activator 1B.
  
 
 
0.978
GUCY2D
Guanylate cyclase.
   
 0.964
A0A287BQK6_PIG
Guanylate cyclase domain-containing protein.
   
 0.895
CNGA1
Cyclic nucleotide gated channel subunit alpha 1.
   
 0.872
PRPH2
Peripherin 2.
   
  
 0.775
A0A5G2Q7C8_PIG
Guanylate cyclase domain-containing protein.
   
 0.764
ARR3
Arrestin-C; May play a role in an as yet undefined retina-specific signal transduction. Could bind to photoactivated-phosphorylated red/green opsins (By similarity).
   
  
 0.672
PDE5A
Phosphodiesterase.
      
 0.649
GUF1
Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.
      
 0.641
CNGB1
Cyclic nucleotide-binding domain-containing protein.
   
 0.627
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.