Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DNPH12'-deoxynucleoside 5'-phosphate N-hydrolase 1; Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases. (182 aa)    
Predicted Functional Partners:
LOC100514465
Uncharacterized protein.
      
 0.895
SERPINB1
Leukocyte elastase inhibitor; Neutrophil serine protease inhibitor that plays an essential role in the regulation of the innate immune response, inflammation and cellular homeostasis. Acts primarily to protect the cell from proteases released in the cytoplasm during stress or infection. These proteases are important in killing microbes but when released from granules, these potent enzymes also destroy host proteins and contribute to mortality. Regulates the activity of the neutrophil proteases elastase, cathepsin G, proteinase-3, chymase, chymotrypsin, and kallikrein-3. Acts also as a [...]
      
 0.787
SERPINB2
Plasminogen activator inhibitor 2; Belongs to the serpin family.
      
 0.786
PRAP1
Uncharacterized protein.
      
 0.702
RUSC1
RUN and SH3 domain-containing protein 1 isoform X1.
      
 0.701
B4GALT2
Beta-1,4-galactosyltransferase 2.
      
 0.697
FN3KRP
Fructosamine 3 kinase related protein; Belongs to the fructosamine kinase family.
      
 0.669
TRNP1
TMF1 regulated nuclear protein 1.
      
 0.628
B4GALT3
Beta-1,4-galactosyltransferase 3.
      
 0.553
SNX1-2
PX domain-containing protein.
      
 0.553
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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