Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TTBK1Tau tubulin kinase 1. (1305 aa)    
Predicted Functional Partners:
NUDCD2
NudC domain containing 2.
    
 
 0.864
CEP164
Centrosomal protein 164.
    
 
 0.653
FAM13A
Family with sequence similarity 13 member A.
      
 0.603
GABARAPL2
Uncharacterized protein.
    
 0.579
GPD1
Glycerol-3-phosphate dehydrogenase [NAD(+)].
      
 0.552
GPAT4
PlsC domain-containing protein.
      
 0.551
CSNK1A1
Casein kinase I isoform alpha; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis. May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration.
   
 0.548
LIMK1
LIM domain kinase 1.
    
 0.541
C20orf194
Chromosome 20 open reading frame 194.
      
 0.534
RIOK2
RIO domain-containing protein.
   
 
 0.531
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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