LRRC73 protein (Sus scrofa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

LRRC73

Leucine-rich repeat-containing protein 73 isoform X1. (316 aa)

Predicted Functional Partners:

TEPSIN

0.855

MARK2

0.700

DOCK3

0.660

KCNMA1

0.580

VSIG10

0.573

POLR3H

0.571

ANKRD13D

0.531

ROBO2

0.511

ANGPT4

0.502

GDF7

0.483

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANGPT4	LRRC73	ENSSSCP00000007666	ENSSSCP00000001823	Angiopoietin 4.	Leucine-rich repeat-containing protein 73 isoform X1.	0.502
ANGPT4	TEPSIN	ENSSSCP00000007666	ENSSSCP00000019542	Angiopoietin 4.	Uncharacterized protein.	0.483
ANKRD13D	LRRC73	ENSSSCP00000074314	ENSSSCP00000001823	Ankyrin repeat domain 13D.	Leucine-rich repeat-containing protein 73 isoform X1.	0.531
ANKRD13D	POLR3H	ENSSSCP00000074314	ENSSSCP00000000069	Ankyrin repeat domain 13D.	DNA-directed RNA polymerase III subunit RPC8 isoform X1.	0.455
ANKRD13D	TEPSIN	ENSSSCP00000074314	ENSSSCP00000019542	Ankyrin repeat domain 13D.	Uncharacterized protein.	0.506
ANKRD13D	VSIG10	ENSSSCP00000074314	ENSSSCP00000031493	Ankyrin repeat domain 13D.	V-set and immunoglobulin domain containing 10.	0.503
DOCK3	LRRC73	ENSSSCP00000044545	ENSSSCP00000001823	Dedicator of cytokinesis 3; Belongs to the DOCK family.	Leucine-rich repeat-containing protein 73 isoform X1.	0.660
DOCK3	MARK2	ENSSSCP00000044545	ENSSSCP00000013878	Dedicator of cytokinesis 3; Belongs to the DOCK family.	Non-specific serine/threonine protein kinase.	0.493
DOCK3	POLR3H	ENSSSCP00000044545	ENSSSCP00000000069	Dedicator of cytokinesis 3; Belongs to the DOCK family.	DNA-directed RNA polymerase III subunit RPC8 isoform X1.	0.509
DOCK3	TEPSIN	ENSSSCP00000044545	ENSSSCP00000019542	Dedicator of cytokinesis 3; Belongs to the DOCK family.	Uncharacterized protein.	0.620
DOCK3	VSIG10	ENSSSCP00000044545	ENSSSCP00000031493	Dedicator of cytokinesis 3; Belongs to the DOCK family.	V-set and immunoglobulin domain containing 10.	0.517
GDF7	LRRC73	ENSSSCP00000021254	ENSSSCP00000001823	Growth differentiation factor 7.	Leucine-rich repeat-containing protein 73 isoform X1.	0.483
GDF7	TEPSIN	ENSSSCP00000021254	ENSSSCP00000019542	Growth differentiation factor 7.	Uncharacterized protein.	0.400
KCNMA1	LRRC73	ENSSSCP00000032909	ENSSSCP00000001823	Calcium-activated potassium channel subunit alpha-1; Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in t [...]	Leucine-rich repeat-containing protein 73 isoform X1.	0.580
KCNMA1	TEPSIN	ENSSSCP00000032909	ENSSSCP00000019542	Calcium-activated potassium channel subunit alpha-1; Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in t [...]	Uncharacterized protein.	0.514
LRRC73	ANGPT4	ENSSSCP00000001823	ENSSSCP00000007666	Leucine-rich repeat-containing protein 73 isoform X1.	Angiopoietin 4.	0.502
LRRC73	ANKRD13D	ENSSSCP00000001823	ENSSSCP00000074314	Leucine-rich repeat-containing protein 73 isoform X1.	Ankyrin repeat domain 13D.	0.531
LRRC73	DOCK3	ENSSSCP00000001823	ENSSSCP00000044545	Leucine-rich repeat-containing protein 73 isoform X1.	Dedicator of cytokinesis 3; Belongs to the DOCK family.	0.660
LRRC73	GDF7	ENSSSCP00000001823	ENSSSCP00000021254	Leucine-rich repeat-containing protein 73 isoform X1.	Growth differentiation factor 7.	0.483
LRRC73	KCNMA1	ENSSSCP00000001823	ENSSSCP00000032909	Leucine-rich repeat-containing protein 73 isoform X1.	Calcium-activated potassium channel subunit alpha-1; Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in t [...]	0.580