Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
PKHD1PKHD1 ciliary IPT domain containing fibrocystin/polyductin. (4075 aa)    
Predicted Functional Partners:
PKD1
Polycystin 1, transient receptor potential channel interacting.
      
 0.832
PKD2
Polycystin 2, transient receptor potential cation channel.
      
 0.825
TMIGD1
Transmembrane and immunoglobulin domain containing 1.
      
 0.668
AP5B1
Adaptor related protein complex 5 subunit beta 1.
    
 
 0.642
PRKCSH
Glucosidase 2 subunit beta isoform X1.
      
 0.641
PMM2
Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions.
      
 0.629
ALG8
Alpha-1,3-glucosyltransferase; Belongs to the ALG6/ALG8 glucosyltransferase family.
      
 0.627
IFT140
Intraflagellar transport 140.
      
 0.577
NPHP3
TPR_REGION domain-containing protein.
   
  
 0.559
RP1L1
Uncharacterized protein.
   
  
 0.552
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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