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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PKHD1PKHD1 ciliary IPT domain containing fibrocystin/polyductin. (4075 aa)    
Predicted Functional Partners:
PKD1
Polycystin 1, transient receptor potential channel interacting.
      
 0.846
PKD2
Polycystin 2, transient receptor potential cation channel.
      
 0.833
AP5B1
Adaptor related protein complex 5 subunit beta 1.
      
 0.751
PMM2
Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions.
      
 0.733
TMIGD1
Transmembrane and immunoglobulin domain containing 1.
      
 0.678
NEK8
NIMA related kinase 8.
      
 0.582
ELF3
E74 like ETS transcription factor 3.
      
 0.572
ARL13B
ADP ribosylation factor like GTPase 13B.
      
 0.572
UMOD
Uromodulin.
    
 
 0.556
AQP2
Aquaporin-2; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
  
 0.550
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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