Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MORF4L1Mortality factor 4-like protein 1 isoform 2. (362 aa)    
Predicted Functional Partners:
MORF4L2
Mortality factor 4 like 2.
  
  
 
0.991
DMAP1
DNA methyltransferase 1-associated protein 1 isoform X1.
    
 0.976
ING3
Inhibitor of growth protein.
   
 0.974
ACTL6A
Actin-like protein 6A isoform X1; Belongs to the actin family.
   
 0.972
BRD8
Bromodomain containing 8.
    
 0.972
EP400
E1A binding protein p400.
    
 0.969
ASH1L
ASH1 like histone lysine methyltransferase.
   
 
 0.961
YEATS2
YEATS domain containing 2.
   
 0.935
ACTL8
Actin like 8; Belongs to the actin family.
   
 0.923
ACTB
Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.
   
 0.923
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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