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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM6SF1Transmembrane 6 superfamily member 1. (402 aa)    
Predicted Functional Partners:
TMEM182
Transmembrane protein 182 isoform a.
      
 0.904
CDH15
Cadherin-15 preproprotein; Cadherins are calcium-dependent cell adhesion proteins.
   
  
 0.818
TSPAN33
Tetraspanin.
      
 0.672
EBPL
EBP like.
      
 0.516
LONRF1
LON peptidase N-terminal domain and RING finger protein 1 isoform 1.
      
 0.503
SIAE
Sialate O-acetylesterase isoform 1.
      
 0.497
HPSE
Heparanase isoform 1 preproprotein.
      
 0.495
ACOT13
Acyl-CoA thioesterase 13.
      
 0.485
GLT8D2
Glycosyltransferase 8 domain-containing protein 2 isoform X1.
      
 0.481
DNASE2
Deoxyribonuclease-2-alpha; Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells (By similarity); Belongs to the DNase II family.
      
 0.474
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.