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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)    
Predicted Functional Partners:
PLXNA1
Plexin A1.
   
 0.918
PLXNA3
Plexin A3.
   
 0.910
PLXNA4
Plexin-A4 isoform X1.
   
 0.910
DPYSL5
Dihydropyrimidinase-related protein 5 isoform X1.
    
 0.901
DPYSL2
Dihydropyrimidinase like 2.
    
 0.901
EZR
Ezrin.
    
 
 0.804
BIN1
Bridging integrator 1.
   
  
 0.650
CRMP1
Collapsin response mediator protein 1.
    
 0.617
TRIAP1
Uncharacterized protein.
      
 0.611
AMPH
Uncharacterized protein.
   
  
 0.607
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.