U2AF1L4 protein (Sus scrofa) - STRING interaction network

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Score

U2AF1L4

Splicing factor U2AF 35 kDa subunit-like protein isoform 2. (247 aa)

Predicted Functional Partners:

U2AF2

0.990

U2AF1

0.901

SF3B4

0.834

SRSF1

0.788

SRSF9

0.772

SRSF2

0.771

SRSF3

0.737

SRSF5

0.692

CHCHD2

0.670

RBM22

0.670

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHCHD2	SF3B4	ENSSSCP00000008270	ENSSSCP00000007108	Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 isoform 1.	Splicing factor 3b subunit 4.	0.540
CHCHD2	U2AF1L4	ENSSSCP00000008270	ENSSSCP00000037692	Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 isoform 1.	Splicing factor U2AF 35 kDa subunit-like protein isoform 2.	0.670
RBM22	SF3B4	ENSSSCP00000024730	ENSSSCP00000007108	RNA binding motif protein 22.	Splicing factor 3b subunit 4.	0.907
RBM22	SRSF1	ENSSSCP00000024730	ENSSSCP00000057405	RNA binding motif protein 22.	Serine/arginine-rich splicing factor 1; Plays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Can stimulate binding of U1 snRNP to a 5'-splice site- containing pre-mRNA. Binds to purine-rich RNA sequences, either the octamer, 5'-RGAAGAAC-3' (r=A or G) or the decamers, AGGACAGAGC/AGGACGAAGC. Binds preferentially to the 5'-CGAGGCG-3' motif in vitro. Three copies of the octame [...]	0.627
RBM22	SRSF5	ENSSSCP00000024730	ENSSSCP00000036224	RNA binding motif protein 22.	Serine and arginine rich splicing factor 5.	0.506
RBM22	SRSF9	ENSSSCP00000024730	ENSSSCP00000010572	RNA binding motif protein 22.	Uncharacterized protein.	0.595
RBM22	U2AF1	ENSSSCP00000024730	ENSSSCP00000044103	RNA binding motif protein 22.	Splicing factor U2AF 35 kDa subunit; Plays a critical role in both constitutive and enhancer- dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron (By similarity).	0.725
RBM22	U2AF1L4	ENSSSCP00000024730	ENSSSCP00000037692	RNA binding motif protein 22.	Splicing factor U2AF 35 kDa subunit-like protein isoform 2.	0.670
RBM22	U2AF2	ENSSSCP00000024730	ENSSSCP00000042718	RNA binding motif protein 22.	U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family.	0.752
SF3B4	CHCHD2	ENSSSCP00000007108	ENSSSCP00000008270	Splicing factor 3b subunit 4.	Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 isoform 1.	0.540
SF3B4	RBM22	ENSSSCP00000007108	ENSSSCP00000024730	Splicing factor 3b subunit 4.	RNA binding motif protein 22.	0.907
SF3B4	SRSF1	ENSSSCP00000007108	ENSSSCP00000057405	Splicing factor 3b subunit 4.	Serine/arginine-rich splicing factor 1; Plays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Can stimulate binding of U1 snRNP to a 5'-splice site- containing pre-mRNA. Binds to purine-rich RNA sequences, either the octamer, 5'-RGAAGAAC-3' (r=A or G) or the decamers, AGGACAGAGC/AGGACGAAGC. Binds preferentially to the 5'-CGAGGCG-3' motif in vitro. Three copies of the octame [...]	0.599
SF3B4	SRSF2	ENSSSCP00000007108	ENSSSCP00000040547	Splicing factor 3b subunit 4.	Serine/arginine-rich splicing factor 2; Necessary for the splicing of pre-mRNA. It is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Binds to purine-rich RNA sequences, either 5'-AGSAGAGTA-3' (S=C or G) or 5 [...]	0.513
SF3B4	SRSF9	ENSSSCP00000007108	ENSSSCP00000010572	Splicing factor 3b subunit 4.	Uncharacterized protein.	0.420
SF3B4	U2AF1L4	ENSSSCP00000007108	ENSSSCP00000037692	Splicing factor 3b subunit 4.	Splicing factor U2AF 35 kDa subunit-like protein isoform 2.	0.834
SF3B4	U2AF2	ENSSSCP00000007108	ENSSSCP00000042718	Splicing factor 3b subunit 4.	U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family.	0.980
SRSF1	RBM22	ENSSSCP00000057405	ENSSSCP00000024730	Serine/arginine-rich splicing factor 1; Plays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Can stimulate binding of U1 snRNP to a 5'-splice site- containing pre-mRNA. Binds to purine-rich RNA sequences, either the octamer, 5'-RGAAGAAC-3' (r=A or G) or the decamers, AGGACAGAGC/AGGACGAAGC. Binds preferentially to the 5'-CGAGGCG-3' motif in vitro. Three copies of the octame [...]	RNA binding motif protein 22.	0.627
SRSF1	SF3B4	ENSSSCP00000057405	ENSSSCP00000007108	Serine/arginine-rich splicing factor 1; Plays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Can stimulate binding of U1 snRNP to a 5'-splice site- containing pre-mRNA. Binds to purine-rich RNA sequences, either the octamer, 5'-RGAAGAAC-3' (r=A or G) or the decamers, AGGACAGAGC/AGGACGAAGC. Binds preferentially to the 5'-CGAGGCG-3' motif in vitro. Three copies of the octame [...]	Splicing factor 3b subunit 4.	0.599
SRSF1	SRSF2	ENSSSCP00000057405	ENSSSCP00000040547	Serine/arginine-rich splicing factor 1; Plays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Can stimulate binding of U1 snRNP to a 5'-splice site- containing pre-mRNA. Binds to purine-rich RNA sequences, either the octamer, 5'-RGAAGAAC-3' (r=A or G) or the decamers, AGGACAGAGC/AGGACGAAGC. Binds preferentially to the 5'-CGAGGCG-3' motif in vitro. Three copies of the octame [...]	Serine/arginine-rich splicing factor 2; Necessary for the splicing of pre-mRNA. It is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Binds to purine-rich RNA sequences, either 5'-AGSAGAGTA-3' (S=C or G) or 5 [...]	0.951
SRSF1	SRSF3	ENSSSCP00000057405	ENSSSCP00000001699	Serine/arginine-rich splicing factor 1; Plays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Can stimulate binding of U1 snRNP to a 5'-splice site- containing pre-mRNA. Binds to purine-rich RNA sequences, either the octamer, 5'-RGAAGAAC-3' (r=A or G) or the decamers, AGGACAGAGC/AGGACGAAGC. Binds preferentially to the 5'-CGAGGCG-3' motif in vitro. Three copies of the octame [...]	Serine and arginine rich splicing factor 3.	0.965