STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PGD6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (481 aa)    
Predicted Functional Partners:
IDNK
idnK, gluconokinase homolog (E. coli); Belongs to the gluconokinase GntK/GntV family
   
 0.996
G6PD
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis
 
 
 0.993
PGLS
6-phosphogluconolactonase
 
 
 0.982
RPIA
Ribose 5-phosphate isomerase A; Belongs to the ribose 5-phosphate isomerase family
  
 
 0.980
TALDO1
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
  
 
 0.963
RPE
Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family
  
 0.960
FN3K
Fructosamine 3 kinase
      
 0.857
GPI
Glucose-6-phosphate isomerase; Besides it's role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons (By similarity)
  
  
 0.843
TKT
Sus scrofa transketolase (TKT), mRNA
  
 
 0.842
TKTL2
Transketolase-like 2
  
 
 0.822
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, Sus scrofa, pig, pigs, swine, wild boar
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