node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CDX2 | FOXA2 | ENSSSCP00000009941 | ENSSSCP00000035009 | Homeobox domain-containing protein. | Hepatocyte nuclear factor 3-beta isoform 1. | 0.834 |
CDX2 | GATA6 | ENSSSCP00000009941 | ENSSSCP00000004009 | Homeobox domain-containing protein. | Transcription factor GATA-6; Transcriptional activator that regulates SEMA3C and PLXNA2. May regulate genes that protect epithelial cells from bacterial infection. Involved in gene regulation specifically in the gastric epithelium. Involved in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. | 0.912 |
CDX2 | NANOG | ENSSSCP00000009941 | ENSSSCP00000056364 | Homeobox domain-containing protein. | Homeobox domain-containing protein. | 0.402 |
CDX2 | POU5F1 | ENSSSCP00000009941 | ENSSSCP00000001474 | Homeobox domain-containing protein. | POU domain, class 5, transcription factor 1; Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. Belongs to the POU transcription factor family. Class-5 subfamily. | 0.866 |
CDX2 | SOX17 | ENSSSCP00000009941 | ENSSSCP00000006669 | Homeobox domain-containing protein. | SRY-box transcription factor 17. | 0.887 |
CDX2 | SOX7 | ENSSSCP00000009941 | ENSSSCP00000040343 | Homeobox domain-containing protein. | Transcription factor SOX-7. | 0.524 |
FOXA2 | CDX2 | ENSSSCP00000035009 | ENSSSCP00000009941 | Hepatocyte nuclear factor 3-beta isoform 1. | Homeobox domain-containing protein. | 0.834 |
FOXA2 | GATA6 | ENSSSCP00000035009 | ENSSSCP00000004009 | Hepatocyte nuclear factor 3-beta isoform 1. | Transcription factor GATA-6; Transcriptional activator that regulates SEMA3C and PLXNA2. May regulate genes that protect epithelial cells from bacterial infection. Involved in gene regulation specifically in the gastric epithelium. Involved in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. | 0.876 |
FOXA2 | NANOG | ENSSSCP00000035009 | ENSSSCP00000056364 | Hepatocyte nuclear factor 3-beta isoform 1. | Homeobox domain-containing protein. | 0.871 |
FOXA2 | POU5F1 | ENSSSCP00000035009 | ENSSSCP00000001474 | Hepatocyte nuclear factor 3-beta isoform 1. | POU domain, class 5, transcription factor 1; Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. Belongs to the POU transcription factor family. Class-5 subfamily. | 0.709 |
FOXA2 | SOX17 | ENSSSCP00000035009 | ENSSSCP00000006669 | Hepatocyte nuclear factor 3-beta isoform 1. | SRY-box transcription factor 17. | 0.887 |
FOXA2 | SOX7 | ENSSSCP00000035009 | ENSSSCP00000040343 | Hepatocyte nuclear factor 3-beta isoform 1. | Transcription factor SOX-7. | 0.614 |
FOXA3 | GATA6 | ENSSSCP00000003348 | ENSSSCP00000004009 | Forkhead box A3. | Transcription factor GATA-6; Transcriptional activator that regulates SEMA3C and PLXNA2. May regulate genes that protect epithelial cells from bacterial infection. Involved in gene regulation specifically in the gastric epithelium. Involved in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. | 0.711 |
FOXA3 | SOX17 | ENSSSCP00000003348 | ENSSSCP00000006669 | Forkhead box A3. | SRY-box transcription factor 17. | 0.435 |
GATA6 | CDX2 | ENSSSCP00000004009 | ENSSSCP00000009941 | Transcription factor GATA-6; Transcriptional activator that regulates SEMA3C and PLXNA2. May regulate genes that protect epithelial cells from bacterial infection. Involved in gene regulation specifically in the gastric epithelium. Involved in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. | Homeobox domain-containing protein. | 0.912 |
GATA6 | FOXA2 | ENSSSCP00000004009 | ENSSSCP00000035009 | Transcription factor GATA-6; Transcriptional activator that regulates SEMA3C and PLXNA2. May regulate genes that protect epithelial cells from bacterial infection. Involved in gene regulation specifically in the gastric epithelium. Involved in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. | Hepatocyte nuclear factor 3-beta isoform 1. | 0.876 |
GATA6 | FOXA3 | ENSSSCP00000004009 | ENSSSCP00000003348 | Transcription factor GATA-6; Transcriptional activator that regulates SEMA3C and PLXNA2. May regulate genes that protect epithelial cells from bacterial infection. Involved in gene regulation specifically in the gastric epithelium. Involved in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. | Forkhead box A3. | 0.711 |
GATA6 | LMCD1 | ENSSSCP00000004009 | ENSSSCP00000060420 | Transcription factor GATA-6; Transcriptional activator that regulates SEMA3C and PLXNA2. May regulate genes that protect epithelial cells from bacterial infection. Involved in gene regulation specifically in the gastric epithelium. Involved in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. | LIM and cysteine-rich domains protein 1; Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6- mediated trans activation of lung- and cardiac tissue-specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter. Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway (By similarity). | 0.925 |
GATA6 | NANOG | ENSSSCP00000004009 | ENSSSCP00000056364 | Transcription factor GATA-6; Transcriptional activator that regulates SEMA3C and PLXNA2. May regulate genes that protect epithelial cells from bacterial infection. Involved in gene regulation specifically in the gastric epithelium. Involved in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. | Homeobox domain-containing protein. | 0.897 |
GATA6 | NKX2-5 | ENSSSCP00000004009 | ENSSSCP00000041789 | Transcription factor GATA-6; Transcriptional activator that regulates SEMA3C and PLXNA2. May regulate genes that protect epithelial cells from bacterial infection. Involved in gene regulation specifically in the gastric epithelium. Involved in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. | NK2 homeobox 5. | 0.727 |