STRINGSTRING
PIK3C3 protein (Sus scrofa) - STRING interaction network
"PIK3C3" - Phosphatidylinositol 3-kinase catalytic subunit type 3 in Sus scrofa
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
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[Homology]
Score
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3 ; Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways- PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Involved in the transport of lysosomal enzyme precursors to lysosomes. Req [...] (887 aa)    
Predicted Functional Partners:
PIK3R4
Uncharacterized protein (1354 aa)
     
  0.997
BECN1
Beclin-1 ; Plays a central role in autophagy. Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways- PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3- C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex forms. In [...] (448 aa)
     
  0.996
ATG14
Uncharacterized protein (492 aa)
     
  0.981
PIKFYVE
Uncharacterized protein (2105 aa)
     
  0.979
PTEN
Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (403 aa)
     
  0.977
BECN2
Uncharacterized protein (437 aa)
     
 
  0.966
ENSSSCG00000011184
Uncharacterized protein (200 aa)
     
 
  0.962
PI4KB
Uncharacterized protein (817 aa)
     
0.949
MTM1
Uncharacterized protein (603 aa)
     
  0.945
MTMR3
Uncharacterized protein (1195 aa)
     
  0.932
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, Suidae, Suiformes, Suina, Sus, Sus scrofa, boars, pig, pigs, swine, wild boar
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