Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AASDH | CYP7A1 | ENSSSCP00000036252 | ENSSSCP00000033898 | Aminoadipate-semialdehyde dehydrogenase. | Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH- ferrihemoprotein reductase). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis. Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha position of cholesterol, a rate-limiting s [...] | 0.511 |
| AASDH | CYP7B1 | ENSSSCP00000036252 | ENSSSCP00000006632 | Aminoadipate-semialdehyde dehydrogenase. | Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. | 0.511 |
| AASDH | F1S3X0_PIG | ENSSSCP00000036252 | ENSSSCP00000004206 | Aminoadipate-semialdehyde dehydrogenase. | Uncharacterized protein. | 0.542 |
| AASDH | FASN | ENSSSCP00000036252 | ENSSSCP00000021647 | Aminoadipate-semialdehyde dehydrogenase. | Uncharacterized protein. | 0.970 |
| AASDH | FDX1 | ENSSSCP00000036252 | ENSSSCP00000033794 | Aminoadipate-semialdehyde dehydrogenase. | Adrenodoxin, mitochondrial; Essential for the synthesis of various steroid hormones. Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage. Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons. Belongs to the adrenodoxin/putidaredoxin family. | 0.420 |
| AASDH | LSS | ENSSSCP00000036252 | ENSSSCP00000035138 | Aminoadipate-semialdehyde dehydrogenase. | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. | 0.505 |
| AASDH | NDUFAB1 | ENSSSCP00000036252 | ENSSSCP00000040903 | Aminoadipate-semialdehyde dehydrogenase. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.985 |
| AASDH | PALB2 | ENSSSCP00000036252 | ENSSSCP00000036943 | Aminoadipate-semialdehyde dehydrogenase. | Partner and localizer of BRCA2. | 0.985 |
| AASDH | SQLE | ENSSSCP00000036252 | ENSSSCP00000006378 | Aminoadipate-semialdehyde dehydrogenase. | Squalene monooxygenase. | 0.436 |
| CYP7A1 | AASDH | ENSSSCP00000033898 | ENSSSCP00000036252 | Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH- ferrihemoprotein reductase). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis. Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha position of cholesterol, a rate-limiting s [...] | Aminoadipate-semialdehyde dehydrogenase. | 0.511 |
| CYP7A1 | F1S3X0_PIG | ENSSSCP00000033898 | ENSSSCP00000004206 | Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH- ferrihemoprotein reductase). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis. Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha position of cholesterol, a rate-limiting s [...] | Uncharacterized protein. | 0.548 |
| CYP7A1 | FASN | ENSSSCP00000033898 | ENSSSCP00000021647 | Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH- ferrihemoprotein reductase). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis. Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha position of cholesterol, a rate-limiting s [...] | Uncharacterized protein. | 0.568 |
| CYP7A1 | FDX1 | ENSSSCP00000033898 | ENSSSCP00000033794 | Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH- ferrihemoprotein reductase). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis. Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha position of cholesterol, a rate-limiting s [...] | Adrenodoxin, mitochondrial; Essential for the synthesis of various steroid hormones. Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage. Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons. Belongs to the adrenodoxin/putidaredoxin family. | 0.462 |
| CYP7A1 | HSD17B7 | ENSSSCP00000033898 | ENSSSCP00000006756 | Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH- ferrihemoprotein reductase). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis. Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha position of cholesterol, a rate-limiting s [...] | Hydroxysteroid 17-beta dehydrogenase 7. | 0.729 |
| CYP7A1 | LSS | ENSSSCP00000033898 | ENSSSCP00000035138 | Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH- ferrihemoprotein reductase). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis. Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha position of cholesterol, a rate-limiting s [...] | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. | 0.841 |
| CYP7A1 | NDUFAB1 | ENSSSCP00000033898 | ENSSSCP00000040903 | Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH- ferrihemoprotein reductase). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis. Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha position of cholesterol, a rate-limiting s [...] | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.414 |
| CYP7A1 | PALB2 | ENSSSCP00000033898 | ENSSSCP00000036943 | Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH- ferrihemoprotein reductase). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis. Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha position of cholesterol, a rate-limiting s [...] | Partner and localizer of BRCA2. | 0.414 |
| CYP7A1 | SQLE | ENSSSCP00000033898 | ENSSSCP00000006378 | Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH- ferrihemoprotein reductase). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis. Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha position of cholesterol, a rate-limiting s [...] | Squalene monooxygenase. | 0.728 |
| CYP7B1 | AASDH | ENSSSCP00000006632 | ENSSSCP00000036252 | Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. | Aminoadipate-semialdehyde dehydrogenase. | 0.511 |
| CYP7B1 | F1S3X0_PIG | ENSSSCP00000006632 | ENSSSCP00000004206 | Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. | Uncharacterized protein. | 0.547 |
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