node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GNAI1 | GNAI2 | ENSSSCP00000016334 | ENSSSCP00000012152 | Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform 1. | G protein subunit alpha i2. | 0.900 |
GNAI1 | GNAI3 | ENSSSCP00000016334 | ENSSSCP00000007279 | Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform 1. | Guanine nucleotide-binding protein G(K) subunit alpha. | 0.901 |
GNAI1 | GNAO1 | ENSSSCP00000016334 | ENSSSCP00000040441 | Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform 1. | Guanine nucleotide-binding protein G(O) subunit alpha isoform b. | 0.638 |
GNAI1 | GNB2 | ENSSSCP00000016334 | ENSSSCP00000008190 | Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform 1. | G protein subunit beta 2. | 0.895 |
GNAI1 | GNB4 | ENSSSCP00000016334 | ENSSSCP00000036910 | Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform 1. | G protein subunit beta 4. | 0.991 |
GNAI1 | GNG2 | ENSSSCP00000016334 | ENSSSCP00000024099 | Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform 1. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.853 |
GNAI1 | OPRM1 | ENSSSCP00000016334 | ENSSSCP00000004401 | Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform 1. | Mu-type opioid receptor; Receptor for endogenous opioids such as beta-endorphin and endomorphin. Receptor for natural and synthetic opioids including morphine, heroin, DAMGO, fentanyl, etorphine, buprenorphin and methadone. Agonist binding to the receptor induces coupling to an inactive GDP-bound heterotrimeric G-protein complex and subsequent exchange of GDP for GTP in the G-protein alpha subunit leading to dissociation of the G-protein complex with the free GTP-bound G-protein alpha and the G-protein beta-gamma dimer activating downstream cellular effectors. The agonist- and cell typ [...] | 0.950 |
GNAI2 | GNAI1 | ENSSSCP00000012152 | ENSSSCP00000016334 | G protein subunit alpha i2. | Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform 1. | 0.900 |
GNAI2 | GNAI3 | ENSSSCP00000012152 | ENSSSCP00000007279 | G protein subunit alpha i2. | Guanine nucleotide-binding protein G(K) subunit alpha. | 0.901 |
GNAI2 | GNAO1 | ENSSSCP00000012152 | ENSSSCP00000040441 | G protein subunit alpha i2. | Guanine nucleotide-binding protein G(O) subunit alpha isoform b. | 0.643 |
GNAI2 | GNB2 | ENSSSCP00000012152 | ENSSSCP00000008190 | G protein subunit alpha i2. | G protein subunit beta 2. | 0.920 |
GNAI2 | GNB4 | ENSSSCP00000012152 | ENSSSCP00000036910 | G protein subunit alpha i2. | G protein subunit beta 4. | 0.988 |
GNAI2 | GNG2 | ENSSSCP00000012152 | ENSSSCP00000024099 | G protein subunit alpha i2. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.848 |
GNAI2 | OPRM1 | ENSSSCP00000012152 | ENSSSCP00000004401 | G protein subunit alpha i2. | Mu-type opioid receptor; Receptor for endogenous opioids such as beta-endorphin and endomorphin. Receptor for natural and synthetic opioids including morphine, heroin, DAMGO, fentanyl, etorphine, buprenorphin and methadone. Agonist binding to the receptor induces coupling to an inactive GDP-bound heterotrimeric G-protein complex and subsequent exchange of GDP for GTP in the G-protein alpha subunit leading to dissociation of the G-protein complex with the free GTP-bound G-protein alpha and the G-protein beta-gamma dimer activating downstream cellular effectors. The agonist- and cell typ [...] | 0.942 |
GNAI3 | GNAI1 | ENSSSCP00000007279 | ENSSSCP00000016334 | Guanine nucleotide-binding protein G(K) subunit alpha. | Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform 1. | 0.901 |
GNAI3 | GNAI2 | ENSSSCP00000007279 | ENSSSCP00000012152 | Guanine nucleotide-binding protein G(K) subunit alpha. | G protein subunit alpha i2. | 0.901 |
GNAI3 | GNAO1 | ENSSSCP00000007279 | ENSSSCP00000040441 | Guanine nucleotide-binding protein G(K) subunit alpha. | Guanine nucleotide-binding protein G(O) subunit alpha isoform b. | 0.638 |
GNAI3 | GNB2 | ENSSSCP00000007279 | ENSSSCP00000008190 | Guanine nucleotide-binding protein G(K) subunit alpha. | G protein subunit beta 2. | 0.927 |
GNAI3 | GNB4 | ENSSSCP00000007279 | ENSSSCP00000036910 | Guanine nucleotide-binding protein G(K) subunit alpha. | G protein subunit beta 4. | 0.992 |
GNAI3 | GNG2 | ENSSSCP00000007279 | ENSSSCP00000024099 | Guanine nucleotide-binding protein G(K) subunit alpha. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.856 |